Boivin Michel, Brendgen Mara, Dionne Ginette, Dubois Lise, Pérusse Daniel, Robaey Philippe, Tremblay Richard E, Vitaro Frank
School of Psychology, Université Laval, Québec, Canada.
Twin Res Hum Genet. 2013 Feb;16(1):64-9. doi: 10.1017/thg.2012.129. Epub 2012 Dec 3.
The Quebec Newborn Twin Study (QNTS) is an ongoing prospective longitudinal follow-up of a birth cohort of twins born between 1995 and 1998 in the greater Montreal area, Québec, Canada. The goal of QNTS is to document individual differences in the cognitive, behavioral, and social-emotional aspects of developmental health across childhood, their early bio-social determinants, as well as their putative role in later social-emotional adjustment, school and health outcomes. A total of 662 families of twins were initially assessed when the twins were aged 6 months. These twins and their family were then followed regularly. QNTS has 14 waves of data collected or planned, including 5 in preschool. Over the past 15 years, a broad range of physiological, cognitive, behavioral, school, and health phenotypes were documented longitudinally through multi-informant and multi-method measurements. QNTS also entails extended and detailed multi-level assessments of proximal (e.g., parenting behaviors, peer relationships) and distal (e.g., family income) features of the child's environment. This detailed longitudinal information makes QNTS uniquely suited for the study of the role of the early years and gene-environment transactions in development.
魁北克新生儿双胞胎研究(QNTS)是一项正在进行的前瞻性纵向随访研究,对象是1995年至1998年在加拿大魁北克大蒙特利尔地区出生的双胞胎队列。QNTS的目标是记录儿童期发育健康在认知、行为和社会情感方面的个体差异、其早期生物社会决定因素,以及它们在后期社会情感适应、学校和健康结果中的假定作用。共有662对双胞胎家庭在双胞胎6个月大时进行了首次评估。然后对这些双胞胎及其家庭进行定期随访。QNTS已收集或计划收集14轮数据,其中包括5轮学前数据。在过去15年中,通过多信息提供者和多方法测量,纵向记录了广泛的生理、认知、行为、学校和健康表型。QNTS还对儿童环境的近端(如养育行为、同伴关系)和远端(如家庭收入)特征进行了扩展和详细的多层次评估。这些详细的纵向信息使QNTS特别适合于研究早年和基因-环境相互作用在发育中的作用。