De Vuyst P, Remmelink M, Mekinda Z, Thimpont J, Dumortier P, Gevenois P-A
Service de pneumologie, hôpital Erasme, université Libre de Bruxelles, 808 route de Lennik, Brussels, Belgium.
Rev Mal Respir. 2012 Nov;29(9):1127-31. doi: 10.1016/j.rmr.2012.04.008. Epub 2012 Jul 23.
A diagnosis of asbestosis, lung fibrosis due to asbestos exposure, was proposed in 2003 in a 64-year-old woman on the basis of the history, computed tomography appearances, lung function studies, and biometric data. This diagnosis was confirmed by the pathological examination of a lung lobe resected surgically for bronchial carcinoma in 2010. The diagnosis of asbestosis is now rarely made as a result of a substantial decrease in dust exposure over the past decades and mainly because of the interdiction of asbestos use in western countries. Currently, the most frequent thoracic manifestations of asbestos exposure are benign pleural lesions and mesothelioma. It has also become exceptional to have pathological confirmation of the diagnosis, obtained in this woman thanks to the surgical treatment of another complication of her occupational exposure.
2003年,根据病史、计算机断层扫描表现、肺功能研究和生物特征数据,对一名64岁女性提出了石棉沉着病(因接触石棉导致的肺纤维化)的诊断。2010年,通过对因支气管癌手术切除的肺叶进行病理检查,证实了这一诊断。由于过去几十年粉尘接触量大幅下降,主要是因为西方国家禁止使用石棉,现在很少做出石棉沉着病的诊断。目前,石棉接触最常见的胸部表现是良性胸膜病变和间皮瘤。通过对该女性职业接触的另一种并发症进行手术治疗而获得病理诊断证实的情况也变得极为罕见。