Biomedical Sciences Research Institute, Unidad de Histología y Anatomía Patológica, Facultad de Veterinaria, Universidad CEU Cardenal Herrera, Avda. Seminario, s/n, 46113 Moncada, Valencia, Spain.
Vet Parasitol. 2013 Mar 31;193(1-3):281-3. doi: 10.1016/j.vetpar.2012.11.018. Epub 2012 Nov 12.
Encephalomyelitis due to Toxoplasma gondii was diagnosed in a fossa (Cryptoprocta ferox). The animal had ataxia, atrophy of hind limb muscles and progressive wasting before dying 12 months after the onset of clinical signs. Toxoplasmosis was suspected antemortem based on clinical signs and the detection of T. gondii DNA by PCR on EDTA-blood from live animal. Necropsy revealed necrotizing gastritis and severe emaciation. The main histological lesions included non-suppurative encephalomyelitis, with dilation of myelin sheaths and swollen axons in the spinal cord, and multifocal gliosis in the brain with intralesional protozoan cysts that stained positive for T. gondii immunohistochemistry. To the authors' knowledge, this is the first report of toxoplasmosis in a fossa, and a new host record.
弓形虫引起的脑脊髓炎被诊断为发生在袋獾（Cryptoprocta ferox）中。该动物出现共济失调、后肢肌肉萎缩，在出现临床症状 12 个月后死亡前逐渐消瘦。根据临床症状以及从活体动物的 EDTA 血液中通过 PCR 检测到 T. gondii DNA，生前怀疑为弓形体病。尸检显示坏死性胃炎和严重消瘦。主要的组织学病变包括非化脓性脑脊髓炎，脊髓中髓鞘扩张和轴突肿胀，大脑多灶性神经胶质增生，伴有内原虫包囊，用 T. gondii 免疫组织化学染色呈阳性。据作者所知，这是袋獾中弓形虫病的首例报告，也是新的宿主记录。
