CICECO and Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Colloids Surf B Biointerfaces. 2013 Mar 1;103:143-8. doi: 10.1016/j.colsurfb.2012.09.045. Epub 2012 Oct 23.
Silver has been mainly investigated as an antibacterial agent and less as a fungicide in which concerns antimicrobial properties. In this research, the antifungal activity of composite films of pullulan and Ag nanoparticles (NP) against Aspergillus niger was evaluated using standard protocols. These new materials were prepared as transparent cast films (66-74 μm thickness) from Ag hydrosols containing the polysaccharide. Fungal growth inhibition was observed in the presence of such silver nanocomposite films. Moreover, disruption of the spores cells of A. niger was probed for the first time by means of scanning electron microscopy (SEM). This effect occurred in the presence of the nanocomposites due to Ag NP dispersed as fillers in pullulan. This polysaccharide was used here as a biocompatible matrix, hence making these nanocomposites beneficial for the development of antifungal packaging materials.
银主要被研究为一种抗菌剂，而较少作为杀菌剂，关注其抗菌性能。在这项研究中，使用标准方案评估了普鲁兰和银纳米粒子（NP）复合膜对黑曲霉的抗真菌活性。这些新材料是由含有多糖的银水溶胶制备而成的透明铸膜（66-74μm 厚）。在存在这种银纳米复合材料的情况下，观察到真菌生长的抑制。此外，首次通过扫描电子显微镜（SEM）探测到黑曲霉孢子细胞的破坏。由于分散在普鲁兰中的 Ag NP 作为填充剂，这种纳米复合材料具有这种作用。这里使用的这种多糖作为生物相容性基质，因此使这些纳米复合材料有益于开发抗真菌包装材料。
