*Rockefeller College of Public Affairs & Policy and †Nelson A. Rockefeller Institute of Government, University at Albany-State University of New York, Albany, NY ‡Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
J Acquir Immune Defic Syndr. 2013 Apr 1;62(4):421-9. doi: 10.1097/QAI.0b013e31827ee56c.
Untreated substance use disorders (SUD) among HIV patients contribute to worse HIV care outcomes and increased HIV transmission. Although there are clinical and policy recommendations for integrated SUD and HIV treatment, payment issues including complex funding streams are a barrier.
We assessed the availability of guideline-concordant medication-assisted therapies to treat alcohol, tobacco, and opioid dependence on state-administered AIDS Drug Assistance Programs (ADAPs), an important source of drug coverage for low-income HIV patients. We examined which medication-assisted therapies are most likely to be included on formularies and variation of these therapies across states.
We reviewed state-specific ADAP formularies from 1997 to 2009 for the presence of guideline-concordant medication-assisted therapies to treat alcohol, tobacco, and opioid dependence.
The most frequently included medication-assisted therapies were those to treat tobacco dependence, followed by opioid dependence. Few states covered alcohol dependence medications. In each year, <10% of states covered all recommended medications and <50% covered a partial formulary for at least 1 SUD.
ADAPs could provide access to medication-assisted therapies for SUD for a significant number of HIV patients, but these medications have not been widely covered throughout the program's history. Increased availability of medication-assisted therapies through ADAP could facilitate integrated HIV and SUD care.
未经治疗的物质使用障碍(SUD)会导致 HIV 患者的 HIV 护理结果恶化,并增加 HIV 传播。尽管有针对 SUD 和 HIV 联合治疗的临床和政策建议,但支付问题(包括复杂的资金流)是一个障碍。
我们评估了在州艾滋病药物援助计划(ADAP)中,治疗酒精、烟草和阿片类药物依赖的符合指南的药物辅助疗法的可用性,这是低收入 HIV 患者药物覆盖的重要来源。我们研究了哪些药物辅助疗法最有可能被列入处方,以及这些疗法在各州的变化情况。
我们回顾了 1997 年至 2009 年各州 ADAP 处方集,以评估是否有治疗酒精、烟草和阿片类药物依赖的符合指南的药物辅助疗法。
最常包括的药物辅助疗法是治疗烟草依赖的药物,其次是治疗阿片类药物依赖的药物。很少有州覆盖治疗酒精依赖的药物。在每一年,不到 10%的州覆盖所有推荐的药物,不到 50%的州至少有部分处方覆盖至少一种 SUD。
ADAP 可以为大量 HIV 患者提供 SUD 的药物辅助疗法,但这些药物在该计划的历史中并未得到广泛覆盖。通过 ADAP 增加药物辅助疗法的可及性,可以促进 HIV 和 SUD 的综合治疗。