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两株耐多药鲍曼不动杆菌的基因组序列,该患者在使用替加环素治疗前后被分离。

Genome sequences of two multidrug-resistant Acinetobacter baumannii strains isolated from a patient before and after treatment with tigecycline.

机构信息

Department of Infectious Diseases, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.

出版信息

J Bacteriol. 2012 Dec;194(24):6979-80. doi: 10.1128/JB.01887-12.

Abstract

Acinetobacter baumannii is a Gram-negative bacterium which emerged as a significant nosocomial pathogen worldwide. To investigate the molecular basis of the tigecycline-resistant mechanism, we determined the genome sequences of two multidrug-resistant A. baumannii strains isolated from a patient before and after treatment with tigecycline.

摘要

鲍曼不动杆菌是一种革兰氏阴性细菌,已成为全球重要的医院获得性病原体。为了研究替加环素耐药机制的分子基础,我们测定了两株从使用替加环素治疗前后的患者中分离的多药耐药鲍曼不动杆菌菌株的基因组序列。

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