Nikiforova T I, Kniazeva T A
Vopr Kurortol Fizioter Lech Fiz Kult. 2012 Sep-Oct(5):11-5.
The present paper is designed to report the results of a clinical study undertaken to estimate the efficacy of artificial silicious-carbon dioxide baths for the rehabilitation and secondary prophylaxis in the patients presenting with arterial hypertension associated with coronary heart disease. The study included 130 patients whose treatment outcome was compared with that in a group of patients treated with the use of ordinary silicious baths alone. It was shown that artificial silicious-carbon dioxide baths have an advantage over the ordinary silicious baths in that they produce a more pronounced therapeutic effect especially in the patients with the most severe forms of hypertension associated with cardiovascular disorders. This effect is due to the combined action of their constituent components, in the first place water soluble silicates and carbon dioxide. The simultaneous action of the water soluble silicon on the structure and permeability of cellular membranes coupled with the reduction of sensitivity of vascular beta-adrenorecepors to pressor agents and inhibition of aldosterone secretion from the adrenal glands under effect of carbon dioxide accounts for the more pronounced hypotensive, anti-ischemic, and antiarrhythmic effect of artificial silicious-carbon dioxide baths that is associated with the beneficial effect on the quality of life in the majority of the treated patients.
本文旨在报告一项临床研究的结果，该研究旨在评估人工硅质 - 二氧化碳浴对伴有冠心病的动脉高血压患者康复和二级预防的疗效。该研究纳入了130名患者，并将其治疗结果与一组仅使用普通硅质浴治疗的患者进行了比较。结果表明，人工硅质 - 二氧化碳浴比普通硅质浴具有优势，因为它们能产生更显著的治疗效果，尤其是在患有与心血管疾病相关的最严重高血压形式的患者中。这种效果归因于其组成成分的联合作用，首先是水溶性硅酸盐和二氧化碳。水溶性硅对细胞膜结构和通透性的同时作用，以及在二氧化碳作用下血管β - 肾上腺素能受体对升压剂敏感性的降低和肾上腺醛固酮分泌的抑制，解释了人工硅质 - 二氧化碳浴更显著的降压、抗缺血和抗心律失常作用，这与对大多数接受治疗患者的生活质量产生有益影响相关。
