Palaoro L A, Rocher A E, Canessa O E, Peressini S, Rosales M, Del Río A G, Mendeluk G
Clinical Biochemistry Department, Clinical Hospital, Buenos Aires University, Buenos Aires, Argentina.
Biotech Histochem. 2013 May;88(3-4):138-44. doi: 10.3109/10520295.2012.741712. Epub 2012 Dec 4.
Hypothyroid rats show alterations in the mobility of sperm recovered from their epididymides. The AgNOR technique, immunohistochemistry and transmission electron microscopy were used to investigate changes in epithelial cells from epididymides of rats treated with (131)I. Counting of NORs did not permit detection of changes in the proliferative capacity of epididymides of hypothyroid animals. Transmission electron microscopy revealed changes in the mitochondria of hypothyroid rats that probably are associated with incipient apoptosis.
甲状腺功能减退的大鼠附睾中回收的精子活动能力出现改变。采用银染核仁组织区（AgNOR）技术、免疫组织化学和透射电子显微镜来研究接受碘-131处理的大鼠附睾上皮细胞的变化。对核仁组织区的计数无法检测出甲状腺功能减退动物附睾增殖能力的变化。透射电子显微镜显示甲状腺功能减退大鼠的线粒体发生变化，这可能与早期细胞凋亡有关。
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