Antonova Mariya L
Department Behavioral Neurobiology, Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Blood Press Monit. 2013 Feb;18(1):32-40. doi: 10.1097/MBP.0b013e32835b9d5f.
The oscillometric method is widely used for noninvasive blood pressure measurement and rarely for assessment of arterial elasticity (volume-to-pressure curve/elastogram) in the systolic (ps)/diastolic (pd) pressure interval. In a wide range of physiologically normal pressures, the elastogram is obtained mostly invasively. In the present study (in two papers), the potential of the oscillometric method for a noninvasive estimation of complete elastogram and blood pressure is examined. The aim of the present first paper is to study the relations between oscillometric arterial volume pulsations and elastogram.
The interactions between transmural pressure, arterial volume pulsations, and elastogram are examined graphically on an idealized model of artery, thereafter proved on experimental oscillometric records (10 patients).
A precise determination of the transmural pressure pulsations at descendent external pressure (as in oscillometry) is presented. The basic relationships between these pulsations and arterial volume pulsations in three specific pressure zones are clarified, which allow a strict dependence to be obtained between the arterial volume pulsations envelope and elastogram. The specific cut-off of transmural pressure and arterial volume pulsations, coincidence of the arterial volume pulsations envelope with the elastogram in the ps/pd interval, and two discontinuities (jumps) of the arterial volume pulsations envelope, at ps and pd, were found. The same was observed by noninvasive arterial oscillometry in humans, with good correspondence to the model excluding narrow intervals around ps and pd, in which the jumps are not clearly distinguishable.
These specific features are assumed as elastogram attributes in the second paper, in which a noninvasive determination of both elastogram and blood pressure is carried out.
示波法广泛用于无创血压测量，而很少用于评估收缩压（ps）/舒张压（pd）区间的动脉弹性（容积-压力曲线/弹性图）。在生理正常血压的广泛范围内，弹性图大多通过有创方式获得。在本研究（两篇论文）中，研究了示波法用于无创估计完整弹性图和血压的潜力。本第一篇论文的目的是研究示波动脉容积搏动与弹性图之间的关系。
在理想化的动脉模型上以图形方式研究跨壁压力、动脉容积搏动和弹性图之间的相互作用，随后在实验示波记录（10例患者）上得到证实。
给出了在外部压力下降时（如在示波测量中）跨壁压力搏动的精确测定。阐明了这三种特定压力区域中这些搏动与动脉容积搏动之间的基本关系，这使得能够在动脉容积搏动包络与弹性图之间获得严格的相关性。发现了跨壁压力和动脉容积搏动的特定截断点、动脉容积搏动包络与ps/pd区间弹性图的重合，以及动脉容积搏动包络在ps和pd处的两个不连续点（跳跃）。在人体无创动脉示波测量中也观察到了同样的情况，与模型具有良好的对应关系，但不包括ps和pd周围的狭窄区间，在这些区间中跳跃不太明显。
在第二篇论文中，这些特定特征被视为弹性图的属性，在该论文中对弹性图和血压进行了无创测定。
