关于葡萄球菌在德国牧羊犬脓皮病（GSP）发病机制中作用的研究。

Investigations on the role of staphylococci in the pathogenesis of German shepherd dog pyoderma (GSP).

作者信息

Wisselink M A, Koeman J P, van den Ingh T S, Willemse A

机构信息

Department of Clinical Sciences of Companion Animals, University of Utrecht, The Netherlands.

出版信息

Vet Q. 1990 Jan;12(1):29-34. doi: 10.1080/01652176.1990.9694238.

DOI:10.1080/01652176.1990.9694238

PMID:2321349

Abstract

Skin reaction patterns to intradermal injections of a Staphylococcus intermedius antigen were examined in physically healthy dogs and in dogs with German Shepherd dog Pyoderma (GSP) at 15 and 30 minutes and at 1, 2, 4, 6, 8, 24, 48 and 72 hours after the injection. In both groups the skin histopathology revealed an aspecific inflammatory response of an early polymorphonuclear reaction, followed by a mononuclear cell reaction at 24 and 48 hours. It is concluded that hypersensitivity to staphylococcal antigens does not play a role in the pathogenesis of GSP.

摘要

对身体健康的犬以及患有德国牧羊犬脓皮病（GSP）的犬进行皮内注射中间葡萄球菌抗原，分别于注射后15分钟、30分钟、1小时、2小时、4小时、6小时、8小时、24小时、48小时和72小时检查皮肤反应模式。在两组中，皮肤组织病理学均显示出早期多形核反应的非特异性炎症反应，随后在24小时和48小时出现单核细胞反应。得出的结论是，对葡萄球菌抗原的超敏反应在GSP的发病机制中不起作用。