Bhandarwar Ajay H, Shaikh Taher A, Borisa Ashok D, Palep Jaydeep H, Patil Arun S, Manke Aditya A
Division of GI and HPP Surgery, Department of Surgery, Grant Medical College & Sir JJ Group of Hospitals, Byculla, Mumbai 400008, India.
Case Rep Surg. 2012;2012:786432. doi: 10.1155/2012/786432. Epub 2012 Nov 18.
Primary Biliary Tract Neuroendocrine tumors (NET) are extremely rare tumors with only 77 cases been reported in the literature till now. We describe a case of a left hepatic duct NET and review the literature for this rare malignancy. To the best of our knowledge the present case is the first reported case of a left hepatic duct NET in the literature. In spite of availability of advanced diagnostic tools like Computerized Tomography (CT) Scan and Endoscopic Retrograde Cholangio Pancreaticography (ERCP) a definitive diagnosis of these tumors is possible only after an accurate histopathologic diagnosis of operative specimens with immunohistochemistry and electron microscopy. Though surgical excision remains the gold standard treatment for such tumors, patients with unresectable tumors have good survival with newer biologic agents like Octreotride.
原发性胆道神经内分泌肿瘤（NET）极为罕见，迄今为止文献中仅报道过77例。我们描述了一例左肝管NET病例，并回顾了关于这种罕见恶性肿瘤的文献。据我们所知，本病例是文献中首次报道的左肝管NET病例。尽管有计算机断层扫描（CT）和内镜逆行胰胆管造影（ERCP）等先进诊断工具，但只有在对手术标本进行准确的组织病理学诊断并结合免疫组织化学和电子显微镜检查后，才能对这些肿瘤做出明确诊断。虽然手术切除仍然是这类肿瘤的金标准治疗方法，但对于无法切除肿瘤的患者，使用奥曲肽等新型生物制剂也有较好的生存率。
