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是否应该通过测量平衡还是步态来更好地预测帕金森病患者跌倒?

Should One Measure Balance or Gait to Best Predict Falls among People with Parkinson Disease?

机构信息

Program in Physical Therapy, Washington University in St. Louis School of Medicine, Campus Box 8502, 4444 Forest Park Boulevard, St. Louis, MO 63108, USA.

出版信息

Parkinsons Dis. 2012;2012:923493. doi: 10.1155/2012/923493. Epub 2012 Oct 31.

Abstract

Introduction. We aimed to determine whether gait velocity is as useful as a balance test, a self-report measure of freezing of gait (FOG), and/or a measure of motor symptom severity for predicting falls among people with Parkinson Disease (PD). Methods. Fifty-six individuals with idiopathic PD completed a baseline assessment consisting of these measures: (1) MDS-UPDRS III, (2) Mini-BESTest, (3) gait velocity (forward, backward, dual task, and fast), and (4) FOGQ. Retrospective fall history was collected at baseline and six months later. Participants were considered fallers if they had two or more falls in the surveillance period. Ability of the tests to discriminate between fallers and nonfallers was determined using ROC curves followed by pairwise statistical noninferiority comparisons (P = .05) of the area under the ROC curve (AUC) for each test. Results. At six months, 22% (n = 21) of the sample were fallers. Fallers differed significantly from nonfallers on the MDS-UPDRS III, Mini-BESTest, backward gait velocity, and FOGQ. The Mini-BESTest had the highest AUC and was superior to all gait velocity measures at identifying fallers. Conclusion. A single measure of gait velocity, even in a challenging condition, may not be as effective as the Mini-BESTest in identifying fallers among people with PD.

摘要

简介。我们旨在确定步态速度是否像平衡测试、冻结步态的自我报告测量(FOG)以及/或运动症状严重程度的测量一样,可用于预测帕金森病(PD)患者的跌倒。方法。56 名特发性 PD 患者完成了一项基线评估,包括以下措施:(1)MDS-UPDRS III,(2)Mini-BESTest,(3)步态速度(向前、向后、双重任务和快速),以及(4)FOGQ。在基线和六个月后收集回顾性跌倒史。如果参与者在监测期内发生两次或更多次跌倒,则被视为跌倒者。使用 ROC 曲线确定了这些测试区分跌倒者和非跌倒者的能力,然后使用 ROC 曲线下的面积(AUC)进行两两统计非劣效性比较(P =.05),以确定每个测试的 AUC。结果。在六个月时,样本中有 22%(n = 21)的人跌倒。跌倒者在 MDS-UPDRS III、Mini-BESTest、向后步态速度和 FOGQ 上与非跌倒者有显著差异。Mini-BESTest 的 AUC 最高,在识别跌倒者方面优于所有步态速度测量。结论。在 PD 患者中,即使是单一的步态速度测量,也可能不如 Mini-BESTest 有效识别跌倒者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b47/3503435/bc4b61aaedd7/PD2012-923493.001.jpg

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