Jakljević Tomislav, Ruzić Alen, Bazdarić Ksenija, Zaputović Luka, Mavrić Zarko, Champagne Stephane, Teiger Emmanuel
University of Rijeka, Rijeka University Hospital Center, Department of Cardiology, Rijeka, Croatia.
Coll Antropol. 2012 Sep;36(3):821-6.
In the study of 286 patients with suspected coronary artery disease and recent exercise single photon emission computed tomography (SPECT) test, we performed coronary angiography with coronary fractional flow reserve (FFR) measurement and tested the differences between diabetic (103) and non-diabetic (183) patients in ischemia detection by this two methods. The diabetic patients had a higher prevalence of hypertension, higher BMI and cholesterol levels, as well as longer duration of hospitalization than non-diabetic patients. There was no difference found between groups according to the exercise SPECT test, but, there were significantly more negative results in the non-diabetic group than in the diabetic group according to the FFR test, also, the percentage of stenosis was higher in diabetic patients. The concordance between the two methods was found, it was fair in diabetic patients (kappa = 0.25, 95% C.I. 0.06-0.45) and moderate in non-diabetic patients (kappa = 0.49, 95% C.I. 0.36-0.62).
在一项针对286例疑似冠心病且近期进行过运动单光子发射计算机断层扫描（SPECT）检查的患者的研究中，我们进行了冠状动脉造影及冠状动脉血流储备分数（FFR）测量，并比较了糖尿病患者（103例）和非糖尿病患者（183例）在通过这两种方法检测缺血情况时的差异。糖尿病患者的高血压患病率更高，体重指数和胆固醇水平更高，住院时间也比非糖尿病患者更长。根据运动SPECT检查，两组之间未发现差异，但根据FFR检查，非糖尿病组的阴性结果显著多于糖尿病组，此外，糖尿病患者的狭窄百分比更高。发现两种方法之间存在一致性，在糖尿病患者中一致性为一般（kappa = 0.25，95%置信区间0.06 - 0.45），在非糖尿病患者中为中等（kappa = 0.49，95%置信区间0.36 - 0.62）。
