Ju Bao-Jun, Niu Lin-Lin
Department of Emergency, The Second Clinical Medical College, Henan University of TCM, Zhengzhou 450003, China.
Zhongguo Zhen Jiu. 2012 Nov;32(11):975-8.
To observe the efficacy differences among acupuncture at Neiguan (PC 6) and Zusanli (ST 36), dolantin and scopolamine in treatment of acute renal colic, and to verify the clinical effect of acupuncture at Neiguan (PC 6) and Zusanli (ST 36).
Two hundred and forty patients were randomly divided into an acupuncture group, a scopolamine group and a dolantin group, 80 cases in each group. The acupuncture group was treated by acupuncture at unilateral or bilateral Neiguan (PC 6) and Zusanli (ST 36). The scopolamine group was treated by intramuscular injection of scopolamine combined with intravenous drip of scopolamine, and the dolantin group was treated by intramuscular injection of dolantin. The clinical therapeutic effects were observed 30 min after drug administration or acupuncture, and the onset time of effect and adverse reactions were compared among the groups.
The total effective rate of 95.0% (76/80) in the acupuncture group had a similar therapeutic effect to 92.5% (74/80) in dolantin group (P>0.05), which were both superior to 76.3% (61/80) in scopolamine group (both P<0.05). The onset time of (13.24 +/- 2.12) min in the acupuncture group was significant earlier than (23.11 +/- 6.22) min in scopolamine group and (22.17 +/- 3.15) min in dolantin group (both P<0.05), and compared with the other two groups, the adverse reactions in the acupuncture group were significant decreased (both P<0.05).
Acupuncture at Neiguan (PC 6) and Zusanli (ST 36) has a good analgesic effect with a low incidence of adverse reactions, which is superior to that of dolantin and scopolamine.
观察针刺内关(PC 6)、足三里(ST 36)与杜冷丁、东莨菪碱治疗急性肾绞痛的疗效差异,验证针刺内关(PC 6)、足三里(ST 36)的临床效果。
将240例患者随机分为针刺组、东莨菪碱组和杜冷丁组,每组80例。针刺组采用针刺单侧或双侧内关(PC 6)、足三里(ST 36)治疗。东莨菪碱组采用肌肉注射东莨菪碱并静脉滴注东莨菪碱治疗,杜冷丁组采用肌肉注射杜冷丁治疗。给药或针刺30分钟后观察临床治疗效果,比较各组起效时间及不良反应。
针刺组总有效率为95.0%(76/80),与杜冷丁组的92.5%(74/80)疗效相似(P>0.05),两者均优于东莨菪碱组的76.3%(61/80)(P均<0.05)。针刺组起效时间为(13.24±2.12)分钟,显著早于东莨菪碱组的(23.11±6.22)分钟和杜冷丁组的(22.17±3.15)分钟(P均<0.05),且与其他两组相比,针刺组不良反应显著减少(P均<0.05)。
针刺内关(PC 6)、足三里(ST 36)镇痛效果良好,不良反应发生率低,优于杜冷丁和东莨菪碱。