Noszczyk-Nowak A
Department of Internal Disease with Clinic of Horses, Dogs and Cats, Faculty of Veterinary Medicine, University of Environmental and Life Sciences, pl. Grunwaldzki 47, 50-366 Wrocław, Poland.
Pol J Vet Sci. 2012;15(3):477-81. doi: 10.2478/v10181-012-0073-8.
Heart rate turbulence (HRT) is a new electrocardiographic parameter used in human medicine to predict the possibility of death in patients with cardiac diseases. There is no information about HRT in healthy dogs and those with cardiac diseases. The aim of the present study was to compare the HRT in healthy Boxers dogs with Boxers with mild and moderate subaortic stenosis (SAS), to disclose the relationship between HRT and specific echocardiographic parameters and to evaluate if HRT can be used as a prognostic value in dogs with aortic stenosis. The study revealed significantly lower values of turbulence onset (TO) and turbulence slope (TS) HRT dogs with SAS (TO = -0.76 +/- 2.6, TS = 7.1 +/- 3.21) in compared with healthy dogs (TO = -7.45 +/- 9.72, TS = 14.33 +/- 8.76). TO values correlated with the left ventricular mass (LVM)/body mass factor (r = 0,32; p = 0.048). Based on the results obtained it can be stated that dogs with SAS have a compromised baroreceptor response, which can influence the mortality of the animals with described cardiac defect.
心率震荡(HRT)是人类医学中用于预测心脏病患者死亡可能性的一项新的心电图参数。目前尚无关于健康犬和患心脏病犬的心率震荡信息。本研究的目的是比较健康拳师犬与患有轻度和中度主动脉瓣下狭窄(SAS)的拳师犬的心率震荡情况,揭示心率震荡与特定超声心动图参数之间的关系,并评估心率震荡是否可作为主动脉狭窄犬的预后指标。研究显示,与健康犬(TO = -7.45 +/- 9.72,TS = 14.33 +/- 8.76)相比,患有SAS的犬的心率震荡起始(TO)和心率震荡斜率(TS)值显著降低(TO = -0.76 +/- 2.6,TS = 7.1 +/- 3.21)。TO值与左心室质量(LVM)/体重因子相关(r = 0.32;p = 0.048)。基于所获得的结果可以表明,患有SAS的犬的压力感受器反应受损,这可能会影响患有所述心脏缺陷的动物的死亡率。