McMillan Sarah K, Knapp Deborah W, Ramos-Vara José A, Bonney Patty L, Adams Larry G
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.
J Am Vet Med Assoc. 2012 Dec 15;241(12):1627-32. doi: 10.2460/javma.241.12.1627.
To determine the outcome in dogs undergoing urethral stent placement for management of urethral obstruction secondary to transitional cell carcinoma (TCC).
Retrospective case series.
19 dogs with histopathologically confirmed TCC.
Information regarding urethral stent placement and follow-up treatment was obtained from review of medical records. Quality of life assessment was performed with an owner questionnaire.
Self-expanding nitinol stents were successfully placed in 17 of 19 dogs; stent placement was not possible in one dog, and another dog was euthanatized 2 days after stent placement, but before discharge from the hospital. Median survival time in 17 dogs following successful long-term stent placement was 78 days (range, 2 to 366 days). Complications following stent placement in 18 dogs included incontinence (n = 7), reobstruction from continued growth of urethral TCC (3), acute reobstruction shortly after the procedure (1), and stent migration (2). Of the 17 owners surveyed, 16 were satisfied with the outcome and would recommend urethral stent placement.
The placement of self-expanding nitinol urethral stents was successful in alleviating TCC-induced urethral obstruction and providing good quality of life for most dogs.
确定接受尿道支架置入术治疗移行细胞癌(TCC)继发尿道梗阻的犬的治疗结果。
回顾性病例系列研究。
19只经组织病理学确诊为TCC的犬。
通过查阅病历获取有关尿道支架置入和后续治疗的信息。采用主人问卷调查进行生活质量评估。
19只犬中有17只成功置入自膨式镍钛合金支架;1只犬无法置入支架,另1只犬在支架置入后2天、出院前实施了安乐死。17只成功长期置入支架的犬的中位生存时间为78天(范围为2至366天)。18只犬支架置入后的并发症包括尿失禁(7只)、尿道TCC持续生长导致的再次梗阻(3只)、术后不久急性再次梗阻(1只)和支架移位(2只)。在接受调查的17位主人中,16位对治疗结果满意,并会推荐尿道支架置入术。
自膨式镍钛合金尿道支架置入术成功缓解了TCC引起的尿道梗阻,并为大多数犬提供了良好的生活质量。