Farnbacher Michael J, Kraupa Werner, Schneider H Thomas
Department of Medicine, Teaching Hospital Klinikum Fuerth, Friedrich-Alexander University Erlangen-Nuremberg, Fuerth, Germany.
J Med Eng Technol. 2013 Jan;37(1):10-6. doi: 10.3109/03091902.2012.728673. Epub 2012 Dec 8.
Occlusion is the major limitation of plastic biliary endoprostheses (PBE), making regular stent exchange necessary. The aim of the in vitro analysis was to evaluate the cleansing effect of shockwave application (SWA) on occluded PBE. Thirty-five PBE removed from 24 patients were analyzed. Three hundred and fifty shockwave pulses were administered every 10 mm along the prosthesis stored in a liquid-filled latex balloon. Occlusion rates were measured before and after SWA. The cleansing rate was calculated in comparison to the native prosthesis. Mean occlusion rate was 76 ± 30% (Range 16-100%) before SWA. Cleansing effect was 47 ± 52% (0-100%) after SWA. Cleaning was complete (100%) in seven (20%) and satisfying (75-99%) in another seven prostheses. Degree of stent occlusion and indwelling time were significantly associated to the cleansing effect. In conclusion, SWA showed a limited cleaning effect in clogged PBE and is no suitable alternative for regular stent replacement to date.
阻塞是塑料胆道内支架（PBE）的主要局限性，这使得定期更换支架成为必要。体外分析的目的是评估冲击波应用（SWA）对阻塞的PBE的清洁效果。对从24例患者中取出的35个PBE进行了分析。沿着储存在充满液体的乳胶气球中的假体，每10毫米施加350个冲击波脉冲。在SWA前后测量阻塞率。与天然假体相比计算清洁率。SWA前平均阻塞率为76±30%（范围16 - 100%）。SWA后清洁效果为47±52%（0 - 100%）。7个（20%）假体的清洁完成率为100%，另外7个假体的清洁效果令人满意（75 - 99%）。支架阻塞程度和留置时间与清洁效果显著相关。总之，SWA对堵塞的PBE清洁效果有限，迄今为止还不是定期更换支架的合适替代方法。
