Department of Obstetrics and Gynecology, Osaka Medical College, 2-7, Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan.
J Ovarian Res. 2012 Dec 5;5(1):41. doi: 10.1186/1757-2215-5-41.
Mature cystic teratomas (MCTs) are the most common germ cell tumors of the ovary. Malignant tranformation occurs in 1-2% of these neoplasms. Although most of the malignancies arising from MCTs are squamous cell carcinomas, adenocarcinoma of the gastrointestinal type is extremery rare. We herein present a case of adenocarcinoma of the intestinal type arising from a MCT.
A 49-year-old female underwent surgery for a left ovarian tumor. The histology of the cyst walls revealed a MCT with a few hair shafts and a squamous layer, while another part of the tumor showed adenocarcinoma of the intestinal type. Five years after surgery, she is alive without disease.
成熟囊性畸胎瘤（MCT）是卵巢最常见的生殖细胞肿瘤。这些肿瘤中有 1%-2%会发生恶性转化。尽管大多数源自 MCT 的恶性肿瘤为鳞状细胞癌，但胃肠道型腺癌极为罕见。本文报告一例源自 MCT 的肠型腺癌。
一名 49 岁女性因左侧卵巢肿瘤接受手术。囊壁的组织学显示为 MCT，有少量毛发和鳞状上皮，而肿瘤的另一部分则表现为肠型腺癌。手术后 5 年，患者无病生存。
