UPS 传递多能性。
UPS delivers pluripotency.
机构信息
Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Fukuoka 812-8582, Japan.
出版信息
Cell Stem Cell. 2012 Dec 7;11(6):728-30. doi: 10.1016/j.stem.2012.11.009.
PMID:23217415
Abstract
In this issue of Cell Stem Cell, Buckley et al. (2012) show that the ubiquitin-proteasome system (UPS) regulates pluripotency in embryonic stem cells and induced pluripotent stem cells, opening the door to a better understanding at the system level of protein dynamics responsible for the maintenance and induction of pluripotency.
摘要
在本期《细胞-干细胞》杂志上，Buckley 等人（2012）表明，泛素-蛋白酶体系统（UPS）调节胚胎干细胞和诱导多能干细胞的多能性，为更好地了解负责维持和诱导多能性的蛋白质动态系统水平打开了大门。
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