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破裂性小脑后下动脉夹层动脉瘤的血管内治疗

Endovascular treatment of ruptured dissecting posterior inferior cerebellar artery aneurysms.

作者信息

Ioannidis I, Nasis N, Andreou A

机构信息

Department of Neurosurgery and Interventional Neuroradiology, "HYGEIA" Hospital, Athens, Greece,

出版信息

Interv Neuroradiol. 2012 Dec;18(4):442-8. doi: 10.1177/159101991201800410. Epub 2012 Dec 3.

Abstract

Dissecting aneurysms of the posterior inferior cerebellar artery (PICA) distal to its origin from vertebral artery (VA) are very rare. Although rare, they associated with a high risk of rebleeding and they present a therapeutic challenge. This study reviewed the clinical presentations, angiographic characteristics of dissecting aneurysms of the PICA and to assess the clinical and angiographic outcomes of patients who underwent endovascular treatment. Ten patients with ten dissecting aneurysms who underwent endovascular treatment were identified in the clinical records of a single medical center from January 2000 to December 2010. The mean follow-up duration was 2.8 years. All patients presented with subarachnoid hemorrhage (SAH). They all underwent endovascular treatment, which included occlusion of the dissected segment and the parent artery after detailed angiographic evaluation of the vascular anatomy, and test occlusion of the PICA. In all patients the endovascular treatment was successfully completed without procedure related complications. Long-term follow-up studies in seven out of ten patients showed complete occlusion of the aneurysm with no new neurologic deficits. The clinical outcome was good in eight cases, whereas two patients with poor clinical condition at admission died during their initial hospital stay. Endovascular occlusion of the parent vessel and the dissected segment is relatively safe treatment option for dissecting aneurysms of the PICA distal to its origin.

摘要

椎动脉(VA)起始部远端的小脑后下动脉(PICA)夹层动脉瘤非常罕见。尽管罕见,但它们与再出血的高风险相关,并且带来了治疗挑战。本研究回顾了PICA夹层动脉瘤的临床表现、血管造影特征,并评估了接受血管内治疗患者的临床和血管造影结果。在一家医疗中心2000年1月至2010年12月的临床记录中,确定了10例患有10个夹层动脉瘤并接受血管内治疗的患者。平均随访时间为2.8年。所有患者均表现为蛛网膜下腔出血(SAH)。他们均接受了血管内治疗,包括在对血管解剖结构进行详细血管造影评估后闭塞夹层段和母动脉,以及对PICA进行试验性闭塞。所有患者均成功完成血管内治疗,无手术相关并发症。10例患者中的7例长期随访研究显示动脉瘤完全闭塞,无新的神经功能缺损。8例患者临床结果良好,而2例入院时临床状况较差的患者在初次住院期间死亡。对于椎动脉起始部远端的PICA夹层动脉瘤,血管内闭塞母血管和夹层段是一种相对安全的治疗选择。

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