激活的 PLCγ 脱逸。
Activated PLCγ breaking loose.
机构信息
Institute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany.
出版信息
Structure. 2012 Dec 5;20(12):1989-90. doi: 10.1016/j.str.2012.11.009.
PMID:23217678
Abstract
In this issue of Structure, Bunney and colleagues use a combination of NMR, SAXS, crystallography, ITC, and biochemical methods to elucidate, in molecular detail, the sequence of events causing receptor-mediated activation of phospholipase C-γ(1) by protein tyrosine phosphorylation.
摘要
本期《结构》杂志中，Bunney 及其同事运用 NMR、SAXS、晶体学、ITC 和生化方法，从分子水平详细阐明了蛋白酪氨酸磷酸化引起的 PLC-γ(1)受体介导的激活过程。
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