Department of Molecular Biology, University of Geneva, Geneva CH-1211, Switzerland.
Structure. 2012 Dec 5;20(12):1993-4. doi: 10.1016/j.str.2012.11.006.
In this issue of Structure, Zhang and colleagues present the structure of the Ego3 dimer, demonstrating that dimerization is an obligate prerequisite in amino acid-induced TORC1 activation.
本期《结构》中,Zhang 及其同事呈现了 Ego3 二聚体的结构,表明二聚化是氨基酸诱导 TORC1 激活的必要前提。