全关节置换术的成本效益:已发表文献的系统评价。

The cost-effectiveness of total joint arthroplasty: a systematic review of published literature.

机构信息

Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA.

出版信息

Best Pract Res Clin Rheumatol. 2012 Oct;26(5):649-58. doi: 10.1016/j.berh.2012.07.013.

Abstract

OBJECTIVE

To summarise the state of the literature evaluating the cost-effectiveness of elective total hip and knee arthroplasty (THA and TKA).

METHODS

We conducted a systematic review of published cost-effectiveness analyses of THA and TKA. To limit our search to high-quality published papers, we selected those papers included in the Cost-Effectiveness Analysis Registry (created by the Center for the Evaluation of Value and Risk in Health at Tufts University) and augmented the search with papers listed in PubMed. The data abstracted included incremental cost-effectiveness ratios, perspective of the analysis, time frame, sensitivity analyses conducted, and utility assessment. All cost-effectiveness ratios were converted to 2011 USD.

RESULTS

Seven studies presenting cost-effectiveness ratios for TKA and six studies for THA were included in our review. All economic evaluations of TKA were published between 2006 and 2012. By contrast, THA studies were published between 1996 and 2008. Out of the 13 studies evaluated in this review, four were from the societal perspective and eight were from the payer perspective. Five studies spanned the lifetime horizon. Of the selected studies, six used probabilistic sensitivity analysis to address uncertainty in data parameters. Both procedures have been shown to be highly cost-effective from the societal perspective over the entire lifespan.

CONCLUSION

THA and TKA have been found to be highly cost-effective in a number of high-quality studies. Further analyses are needed on the cost-effectiveness of alternative surgical options, particularly osteotomy. Future economic evaluations should address the expanding indications of THA and TKA to younger, more physically active individuals.

摘要

目的

总结评估选择性全髋关节和膝关节置换术(THA 和 TKA)成本效益的文献现状。

方法

我们对 THA 和 TKA 的成本效益分析进行了系统综述。为了将搜索范围限制在高质量的已发表论文中,我们选择了那些被 Tufts 大学价值评估与风险中心(Center for the Evaluation of Value and Risk in Health at Tufts University)的成本效益分析登记处(Cost-Effectiveness Analysis Registry)收录的论文,并通过 PubMed 列出的论文对搜索进行了补充。提取的数据包括增量成本效益比、分析视角、时间范围、进行的敏感性分析和效用评估。所有成本效益比均转换为 2011 年美元。

结果

我们的综述纳入了 7 项关于 TKA 的成本效益比研究和 6 项关于 THA 的研究。所有关于 TKA 的经济评估都发表于 2006 年至 2012 年期间。相比之下,THA 的研究发表于 1996 年至 2008 年期间。在本综述评估的 13 项研究中,有 4 项从社会角度进行评估,8 项从支付者角度进行评估。有 5 项研究跨越了整个生命周期。在选定的研究中,有 6 项使用概率敏感性分析来处理数据参数的不确定性。从社会角度来看,这两种手术在整个生命周期内都被证明是高度成本效益的。

结论

在多项高质量研究中,THA 和 TKA 被发现具有高度的成本效益。需要进一步分析替代手术选择的成本效益,特别是截骨术。未来的经济评估应针对 THA 和 TKA 向更年轻、更活跃的个体扩大适应证的情况。

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