Optics Research Group, Optics Department, Faculty of Physics, University of Valencia, Valencia, Spain.
Am J Ophthalmol. 2013 Mar;155(3):499-507.e1. doi: 10.1016/j.ajo.2012.09.031. Epub 2012 Dec 4.
To evaluate visual and optical quality of the implantable collamer lens for different powers and sizes of incision surgery.
Prospective study in humans.
An adaptive optics visual simulator was used to measure 3 powers of implantable collamer lenses and simulate the implantable collamer lens wavefront aberration's pattern for small- and large-incision surgery. Visual acuity (VA) and contrast sensitivity were measured in 11 observers for 3- and 5-mm pupils. Modulation transfer function, point spread function, and Strehl ratio were calculated.
At 3 mm pupil, no statistically significant differences were found between both incision sizes for any implantable collamer lens power, except for -15 diopter (D) implantable collamer lens at 25 cycles/degree (cpd) (P < .05). At 5 mm pupil, statistically significant differences in Strehl ratio, VA, and contrast sensitivity were found between both incision sizes for all implantable collamer lens powers (P < .05). The outcomes were better with small incision. Implantable collamer lens power also affected the optical and visual quality. At 3 mm pupil, no statistically significant differences were found in VA and contrast sensitivity between implantable collamer lens powers, except between -3 and -15 D at low-contrast VA and at 20 and 25 cpd (P < .05). At 5 mm pupil, no statistically significant differences were found in Strehl ratio, VA, and contrast sensitivity between -3 and -6 D implantable collamer lens, but they did become apparent for -15 D implantable collamer lens for both incision sizes, all contrasts and spatial frequencies (P < .05).
The implantable collamer lens provides good optical and visual quality, although these outcomes decreased with large-incision surgery because of the increase of aberrations.
评估不同切口大小和手术方式的可植入式 Collamer 透镜的视觉和光学质量。
前瞻性人体研究。
使用自适应光学视觉模拟器测量三种不同屈光度的可植入式 Collamer 透镜，并模拟小切口和大切口手术的可植入式 Collamer 透镜波前像差模式。在 11 名观察者中测量 3 毫米和 5 毫米瞳孔的视力（VA）和对比敏感度。计算调制传递函数、点扩散函数和斯特列尔比。
在 3 毫米瞳孔下，除 25 周/度（cpd）的-15 屈光度（D）可植入式 Collamer 透镜外，两种切口大小之间的任何可植入式 Collamer 透镜屈光度均无统计学差异（P<0.05）。在 5 毫米瞳孔下，所有可植入式 Collamer 透镜屈光度的两种切口大小之间的斯特列尔比、VA 和对比敏感度均有统计学差异（P<0.05）。小切口的结果更好。可植入式 Collamer 透镜屈光度也影响光学和视觉质量。在 3 毫米瞳孔下，除低对比度 VA 的-3 和-15 D 之间以及 20 和 25 cpd 之间外（P<0.05），VA 和对比敏感度在可植入式 Collamer 透镜屈光度之间无统计学差异。在 5 毫米瞳孔下，-3 和-6 D 可植入式 Collamer 透镜之间的斯特列尔比、VA 和对比敏感度无统计学差异，但对于两种切口大小、所有对比度和空间频率的-15 D 可植入式 Collamer 透镜，差异变得明显（P<0.05）。
可植入式 Collamer 透镜提供良好的光学和视觉质量，但由于像差增加，大切口手术会降低这些结果。
