Targarona Javier, Barreda Luis, Pando Elizabeth, Barreda Claudia
Departamento de Cirugía General, Hospital Edgardo Rebagliati Martins, Lima, Perú.
Cir Esp. 2013 Mar;91(3):163-8. doi: 10.1016/j.ciresp.2012.04.010. Epub 2012 Dec 6.
The pancreatic fistula is the most feared complication after a duodenopancreatectomy, and is the most common independent factor of post-surgical mortality. Peng et al. recently published a pancreaticojejunal anastomosis technique (binding anastomosis) which showed 0% pancreatic fistulas. The objective of this study is to evaluate and validate this new anastomosis technique compared with the conventional pancreaticoduodenectomy with end-to-side duct-to-mucosa anastomosis.
A prospective, non-randomised study was conducted to evaluate and validate this new anastomosis technique compared with the conventional pancreaticojejunal terminolateral duct to mucosa anastomosis. The study included 63 patients who were subjected to a duodenopancreatectomy due to having a pancreatic or periampullary neoplasm. A binding pancreaticojejunostomy according to the technique described by Peng et al. was performed on 30 patients (Group A), and a pancreaticoduodenectomy with end-to-side duct-to-mucosa anastomosis (conventional technique) was performed on 33 patients (Group B).
When the results of the 2 techniques were compared, 2/30 (6%) of patients had a pancreatic fistula with the Peng technique, and 4/33 (12%) with the conventional technique, but this was not statistically significant (P=.674). Nor were there any significant differences between the 2 groups on comparing, morbidity, hospital stay and mortality.
The results of this study show that the anastomosis method described by Peng is safe, but is not associated with a lower frequency of pancreatic fistula, general morbidity, or mortality. This leads to the uncertainty of whether it really has any advantages over other techniques.
胰瘘是十二指肠胰切除术后最令人担忧的并发症,也是术后死亡的最常见独立因素。彭等人最近发表了一种胰空肠吻合技术(捆绑吻合术),该技术显示胰瘘发生率为0%。本研究的目的是将这种新的吻合技术与传统的胰十二指肠切除术(端侧胰管对黏膜吻合术)进行比较,以评估和验证该技术。
进行了一项前瞻性、非随机研究,将这种新的吻合技术与传统的胰空肠端侧胰管对黏膜吻合术进行比较,以评估和验证该技术。该研究纳入了63例因胰腺或壶腹周围肿瘤接受十二指肠胰切除术的患者。对30例患者(A组)采用彭等人描述的技术进行捆绑式胰空肠吻合术,对33例患者(B组)采用胰十二指肠切除术并进行端侧胰管对黏膜吻合术(传统技术)。
比较两种技术的结果时,采用彭氏技术的患者中有2/30(6%)发生胰瘘,采用传统技术的患者中有4/33(12%)发生胰瘘,但差异无统计学意义(P = 0.674)。两组在比较发病率、住院时间和死亡率方面也没有显著差异。
本研究结果表明,彭氏描述的吻合方法是安全的,但与较低的胰瘘发生率、总体发病率或死亡率无关。这导致了该技术相对于其他技术是否真的具有优势的不确定性。