Department of Anesthesiology, University of Pittsburgh, 200 Lothrop St, Pittsburgh, PA 15213, USA.
Spine J. 2012 Dec;12(12):1103-10. doi: 10.1016/j.spinee.2012.10.027. Epub 2012 Dec 7.
To date, many studies have examined the effects of one or several factors on blood loss during lumbar spine surgery. The nature and extent of the operation, patient position, blood pressure, and a variety of factors related to patient size have been touted as predictors of blood loss.
To measure multiple factors implicated as determinants of blood loss and develop a multivariable statistical model capable of predicting blood loss.
An observational study of patients undergoing lumbar spine surgery in the prone position on the Jackson table.
A total of 71 healthy adult men and women undergoing lumbar spine surgery in a university hospital setting.
Blood loss during surgery.
We observed 35 surgeries and recorded demographic and body habitus data on each patient as well as surgical variables, blood pressure, and peripheral venous pressure. We measured bladder pressure intermittently as a surrogate for intra-abdominal pressure. We constructed a statistical model with the results and validated that model in a separate set of 36 subjects.
The Jackson table supported all our patients regardless of body dimensions without causing an increase in bladder pressure. Blood loss during surgery averaged 1,167±998 mL (mean±1 standard deviation, range 32-3,745). The statistical model was able to account for about 75% of the variability in blood loss using four variables: the number of laminectomies, whether bone was harvested from the iliac crest, experience of the surgeon doing the initial exposure and closure, and distension of the epidural veins. Data on these variables that were collected in the validation study found a multiple correlation coefficient (R(2)) of 0.66 between predicted and observed blood loss.
This is the first study to build a successful multivariable predictive model of blood loss during spine surgery. The Jackson table was effective in supporting patients with different body sizes and shapes, thus removing raised intra-abdominal pressure as an important factor.
迄今为止,许多研究已经检验了一个或多个因素对腰椎手术失血的影响。手术的性质和范围、患者体位、血压以及与患者体型相关的各种因素都被认为是失血的预测因素。
测量多种被认为是失血决定因素的因素,并开发一个能够预测失血的多变量统计模型。
对在杰克逊手术台上俯卧位接受腰椎手术的患者进行的观察性研究。
共 71 名在大学医院环境中接受腰椎手术的健康成年男女。
手术期间的失血量。
我们观察了 35 例手术,并记录了每位患者的人口统计学和体型数据以及手术变量、血压和外周静脉压。我们间歇性测量膀胱压作为腹腔内压的替代指标。我们根据结果构建了一个统计模型,并在另一组 36 名患者中验证了该模型。
杰克逊手术台能够支撑我们的所有患者,无论体型如何,都不会导致膀胱压升高。手术期间的失血量平均为 1167±998ml(平均值±1 个标准差,范围 32-3745)。该统计模型能够使用四个变量解释约 75%的失血量变化:行椎板切除术的数量、是否从髂嵴取骨、进行初始暴露和关闭的外科医生的经验以及硬脊膜静脉扩张。在验证研究中收集的这些变量的数据发现,预测和观察到的失血量之间的多元相关系数(R2)为 0.66。
这是第一项构建脊柱手术失血多变量预测模型的研究。杰克逊手术台能够有效地支撑体型不同的患者,从而消除了升高的腹腔内压这一重要因素。