Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan.
Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan.
J Thorac Cardiovasc Surg. 2014 Jan;147(1):307-11. doi: 10.1016/j.jtcvs.2012.11.015. Epub 2012 Dec 6.
The management strategy for type A acute aortic dissection (AAD) with intramural hematoma (IMH) remains controversial. The aim of this study was to compare the outcomes of emergency surgery and medical treatment for patients with acute type A IMH.
One hundred seventy-one patients with acute type A IMH, whose average age was 69.4 years (range, 39-90 years) were divided into 3 groups: groups I and II consisted of 74 and 33 patients undergoing emergency surgery for complicated and uncomplicated type A IMH, respectively, and group III comprised 66 patients who were treated conservatively. We compared the 3 groups in terms of mortality and morbidity.
In group I, postoperative hospital mortality was 5.4% (4 patients). In group II, all patients survived without any complications after surgery. On the other hand, in group III, 5 patients underwent emergency surgery within 7 days after onset owing to newly developed cardiac tamponade and 17 (25.8%) patients died in the hospital, which was a significantly higher rate than those in groups I and II. Furthermore, although the group III patients survived, 5 patients required mechanical ventilation owing to heart failure or pneumonia, and 4 patients had a stroke during the hospital stay. There was no difference in actuarial survivals at 10 years, which were 64.2% in group I, 64.9% in group II, and 68.7% in group III.
Emergency surgery for patients with type A IMH showed favorable mortality rates because most of the patients were in hemodynamically stable condition preoperatively. On the other hand, several patients died suddenly during medical care. Emergency surgical treatment may provide a better outcome than medical treatment at the time of onset, even for patients with type A IMH.
急性 A 型主动脉夹层(AAD)伴壁内血肿(IMH)的治疗策略仍存在争议。本研究旨在比较急性 A 型 IMH 患者行急诊手术与内科治疗的预后。
171 例急性 A 型 IMH 患者,平均年龄 69.4 岁(范围 39-90 岁),分为 3 组:I 组和 II 组分别为 74 例和 33 例因复杂和不复杂的 A 型 IMH 而行急诊手术,III 组 66 例患者行内科治疗。比较 3 组患者的死亡率和发病率。
I 组术后院内死亡率为 5.4%(4 例)。II 组所有患者术后均无并发症存活。另一方面,III 组中有 5 例患者因新发心脏压塞在发病后 7 天内行急诊手术,17 例(25.8%)患者院内死亡,明显高于 I 组和 II 组。此外,尽管 III 组患者存活,但有 5 例因心力衰竭或肺炎需机械通气,4 例在住院期间发生卒中。10 年生存率无差异,I 组为 64.2%,II 组为 64.9%,III 组为 68.7%。
A 型 IMH 患者行急诊手术死亡率较低,因为大多数患者术前血流动力学稳定。另一方面,一些患者在内科治疗期间突然死亡。即使对于 A 型 IMH 患者,发病时行急诊手术治疗可能比内科治疗预后更好。