• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

持续隐神经阻滞作为单次局部浸润镇痛在全膝关节置换术后疼痛管理中的补充。

Continuous saphenous nerve block as supplement to single-dose local infiltration analgesia for postoperative pain management after total knee arthroplasty.

机构信息

Department of Anaesthesia, Copenhagen University Hospital, Frederiksberg, Denmark.

出版信息

Reg Anesth Pain Med. 2013 Mar-Apr;38(2):106-11. doi: 10.1097/AAP.0b013e31827900a9.

DOI:10.1097/AAP.0b013e31827900a9
PMID:23222363
Abstract

BACKGROUND AND OBJECTIVES

Local infiltration analgesia (LIA) reduces pain after total knee arthroplasty without the motor blockade associated with epidural analgesia or femoral nerve block. However, the duration and efficacy of LIA are not sufficient. A saphenous nerve block, in addition to single-dose LIA, may improve analgesia without interfering with early mobilization.

METHODS

Forty patients were included in this double-blind randomized controlled trial. All patients received spinal anesthesia for surgery and single-dose LIA during the operation. An ultrasound-guided saphenous nerve catheter was placed postoperatively in the adductor canal at midthigh level. Patients were randomized into 2 groups to receive 15-mL boluses of either ropivacaine 7.5 mg/mL or saline twice daily for 2 postoperative days.

RESULTS

Worst pain scores during movement on the day of surgery were significantly lower in the ropivacaine group (median [range] visual analog scale, 3 [0-7] vs 5.5 [0-10]; P < 0.050), as well as pain at rest (visual analog scale, 2 [0-8] vs 4 [0-8]; P = 0.032). Breakthrough pain occurred later in the ropivacaine group (10.5 [range, 0.5-48] hours vs 3.4 [range, 0.5-24] hours; P = 0.011). All patients in the ropivacaine group were able to ambulate on the day of surgery versus 13 patients in the control group (P = 0.004). Fewer patients had sleep disturbance on the first postoperative night in the ropivacaine group (P = 0.038). We found no differences in morphine consumption.

CONCLUSIONS

The combination of a saphenous nerve block with single-dose LIA offered better pain relief on the day of surgery than LIA alone.

摘要

背景与目的

局部浸润镇痛(LIA)可减轻全膝关节置换术后的疼痛,且不会产生与硬膜外镇痛或股神经阻滞相关的运动阻滞。然而,LIA 的持续时间和效果并不足够。在单次 LIA 的基础上增加隐神经阻滞可能会改善镇痛效果,同时不影响早期活动。

方法

本双盲随机对照试验纳入了 40 名患者。所有患者在手术中均接受了脊髓麻醉和术中单次 LIA。术后在大腿中高位的收肌管内放置超声引导的隐神经导管。患者随机分为两组,术后 2 天内每天接受 2 次 15 mL 的罗哌卡因 7.5 mg/mL 或生理盐水推注。

结果

手术当天活动时的最差疼痛评分在罗哌卡因组显著降低(中位数[范围]视觉模拟评分,3[0-7] vs 5.5[0-10];P<0.050),休息时的疼痛也较低(视觉模拟评分,2[0-8] vs 4[0-8];P=0.032)。罗哌卡因组出现爆发性疼痛的时间较晚(10.5[范围,0.5-48]小时 vs 3.4[范围,0.5-24]小时;P=0.011)。与对照组相比,所有罗哌卡因组的患者在手术当天均能行走(P=0.004)。罗哌卡因组在术后第一晚睡眠障碍的患者较少(P=0.038)。我们未发现两组间吗啡消耗的差异。

结论

隐神经阻滞联合单次 LIA 比单独使用 LIA 在手术当天能提供更好的镇痛效果。

相似文献

1
Continuous saphenous nerve block as supplement to single-dose local infiltration analgesia for postoperative pain management after total knee arthroplasty.持续隐神经阻滞作为单次局部浸润镇痛在全膝关节置换术后疼痛管理中的补充。
Reg Anesth Pain Med. 2013 Mar-Apr;38(2):106-11. doi: 10.1097/AAP.0b013e31827900a9.
2
Relative Contributions of Adductor Canal Block and Intrathecal Morphine to Analgesia and Functional Recovery After Total Knee Arthroplasty: A Randomized Controlled Trial.股神经阻滞联合鞘内吗啡对全膝关节置换术后镇痛和功能恢复的相对作用:一项随机对照试验。
Reg Anesth Pain Med. 2018 Feb;43(2):154-160. doi: 10.1097/AAP.0000000000000724.
3
Local infiltration analgesia versus intrathecal morphine for postoperative pain management after total knee arthroplasty: a randomized controlled trial.局部浸润镇痛与鞘内吗啡用于全膝关节置换术后疼痛管理的随机对照试验。
Anesth Analg. 2011 Oct;113(4):926-33. doi: 10.1213/ANE.0b013e3182288deb. Epub 2011 Aug 4.
4
Single-Dose Adductor Canal Block With Local Infiltrative Analgesia Compared With Local Infiltrate Analgesia After Total Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.全膝关节置换术后单剂量收肌管阻滞联合局部浸润镇痛与单纯局部浸润镇痛的比较:一项随机、双盲、安慰剂对照试验
Reg Anesth Pain Med. 2016 Nov-Dec;41(6):678-684. doi: 10.1097/AAP.0000000000000494.
5
Adductor canal block versus femoral nerve block for analgesia after total knee arthroplasty: a randomized, double-blind study.收肌管阻滞与股神经阻滞用于全膝关节置换术后镇痛的随机、双盲研究。
Reg Anesth Pain Med. 2013 Nov-Dec;38(6):526-32. doi: 10.1097/AAP.0000000000000015.
6
Continuous adductor canal block added to local infiltration analgesia (LIA) after total knee arthroplasty has no additional benefits on pain and ambulation on postoperative day 1 and 2 compared with LIA alone.全膝关节置换术后,与单纯局部浸润镇痛(LIA)相比,持续收肌管阻滞联合LIA在术后第1天和第2天对疼痛和行走能力并无额外益处。
Acta Orthop. 2017 Oct;88(5):537-542. doi: 10.1080/17453674.2017.1342184. Epub 2017 Jun 19.
7
Pain After Unilateral Total Knee Arthroplasty: A Prospective Randomized Controlled Trial Examining the Analgesic Effectiveness of a Combined Adductor Canal Peripheral Nerve Block with Periarticular Infiltration Versus Adductor Canal Nerve Block Alone Versus Periarticular Infiltration Alone.单侧全膝关节置换术后疼痛:一项前瞻性随机对照试验,比较内收肌管周围神经阻滞联合关节周围浸润、单纯内收肌管神经阻滞及单纯关节周围浸润的镇痛效果。
Anesth Analg. 2016 Jun;122(6):2040-6. doi: 10.1213/ANE.0000000000001210.
8
Intraarticular analgesia versus epidural plus femoral nerve block after TKA: a randomized, double-blind trial.关节内镇痛与 TKA 后硬膜外联合股神经阻滞:一项随机、双盲试验。
Clin Orthop Relat Res. 2014 May;472(5):1400-8. doi: 10.1007/s11999-013-3351-6.
9
Single-injection or continuous femoral nerve block for total knee arthroplasty?单次注射或连续股神经阻滞用于全膝关节置换术?
Clin Orthop Relat Res. 2014 May;472(5):1384-93. doi: 10.1007/s11999-013-3192-3.
10
Local infiltration anaesthesia versus sciatic nerve and adductor canal block for fast-track knee arthroplasty: A randomised controlled clinical trial.局部浸润麻醉与坐骨神经和收肌管阻滞用于快速通道膝关节置换术:一项随机对照临床试验。
Eur J Anaesthesiol. 2019 Apr;36(4):255-263. doi: 10.1097/EJA.0000000000000929.

引用本文的文献

1
Analgesic effect of local anesthesia in total knee arthroplasty: protocol of a randomized controlled clinical trial.全膝关节置换术中局部麻醉的镇痛效果:一项随机对照临床试验方案
Int J Surg Protoc. 2025 Aug 7;29(3):122-127. doi: 10.1097/SP9.0000000000000056. eCollection 2025 Sep.
2
Adductor canal block in total knee arthroplasty: a scoping review of the literature.全膝关节置换术中的收肌管阻滞:文献综述
BJA Open. 2025 Mar 18;14:100381. doi: 10.1016/j.bjao.2025.100381. eCollection 2025 Jun.
3
The effect of adductor canal block on outcomes of total knee arthroplasty: A single centre, historical cohort study.
收肌管阻滞对全膝关节置换术结局的影响:一项单中心历史队列研究。
J Orthop. 2024 Dec 11;65:31-35. doi: 10.1016/j.jor.2024.12.008. eCollection 2025 Jul.
4
The Effect of Postoperative Single-Injection Adductor Canal Block in Total Knee Arthroplasty Under Spinal Anesthesia With Intraoperative Dexmedetomidine Infusion.术中输注右美托咪定的脊髓麻醉下全膝关节置换术后单次注射内收肌管阻滞的效果
Arthroplast Today. 2024 Apr 17;27:101366. doi: 10.1016/j.artd.2024.101366. eCollection 2024 Jun.
5
A randomized controlled trial on the effectiveness of laparoscopic-guided transversus abdominis plane block in patients undergoing laparoscopic IPOM plus.腹腔镜引导下腹横肌平面阻滞对腹腔镜 IPOM 加手术患者有效性的随机对照试验。
Hernia. 2024 Aug;28(4):1257-1263. doi: 10.1007/s10029-024-03016-w. Epub 2024 Mar 23.
6
Does Proximal Adductor Canal Block Provide Better Analgesic Efficacy than Distal Adductor Canal Block in Patients Undergoing Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.内侧收肌管阻滞与外侧收肌管阻滞用于膝关节置换术患者的镇痛效果比较:一项随机对照试验的系统评价和荟萃分析。
Orthop Surg. 2024 May;16(5):1019-1033. doi: 10.1111/os.14027. Epub 2024 Mar 20.
7
Efficacy of Supplemental Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block in Patients Receiving Local Infiltration Analgesia after Hip Fracture Surgery: A Prospective Randomized Controlled Trial.超声引导下囊周神经群(PENG)阻滞联合股外侧皮神经阻滞用于髋部骨折术后患者局部浸润镇痛的效果:一项前瞻性随机对照试验。
Medicina (Kaunas). 2024 Feb 12;60(2):315. doi: 10.3390/medicina60020315.
8
Peripheral regional anaesthesia and outcomes: a narrative review of the literature from 2013 to 2023.外周区域麻醉与结局:2013 年至 2023 年文献的叙述性综述。
Br J Anaesth. 2024 May;132(5):1082-1096. doi: 10.1016/j.bja.2023.10.013. Epub 2023 Nov 11.
9
A prospective comparative study of local infiltration versus adductor block versus combined use of the two techniques following knee arthroplasty.膝关节置换术后局部浸润与内收肌阻滞及两种技术联合应用的前瞻性对比研究。
Arthroplasty. 2020 May 20;2(1):15. doi: 10.1186/s42836-020-00034-8.
10
Analgesic efficacy of single-shot adductor canal block versus adductor canal block combined with intra-articular ropivacaine infusion after total knee arthroplasty.全膝关节置换术后单次股内收肌管阻滞与股内收肌管阻滞联合关节腔内注射罗哌卡因的镇痛效果比较
Bone Jt Open. 2021 Dec;2(12):1082-1088. doi: 10.1302/2633-1462.212.BJO-2021-0119.R1.