Grazi E, Trombetta G, Guidoboni M
Istituto di Chimica Biologica, Università di Ferrara, Italy.
Biochem Biophys Res Commun. 1990 Mar 30;167(3):1109-14. doi: 10.1016/0006-291x(90)90637-3.
Filamin increases and tropomyosin decreases the susceptibility of F-actin to form bundles of filaments in the presence of polyethylene glycol 6000. The two proteins, which are located in the leading edge and in the internal part of the cell, respectively, are thus likely to display divergent effects on the microfilaments into bundles transition in these two areas of the cell.
在聚乙二醇6000存在的情况下,细丝蛋白会增加而原肌球蛋白会降低F-肌动蛋白形成丝状束的敏感性。这两种蛋白分别位于细胞前缘和内部,因此可能在细胞的这两个区域对微丝束化转变产生不同的影响。