Kaufman T, Lusthaus S N, Sagher U, Wexler M R
Department of Plastic Surgery, Hadassah University Hospital, Ein Kerem, Jerusalem, Israel.
Burns. 1990 Feb;16(1):13-6. doi: 10.1016/0305-4179(90)90199-7.
A reproducible deep partial skin thickness burn model using guinea-pigs to study the healing process of this injury is described. Round aluminium templates heated to 75 degrees C and applied for 5 s to the moistened, clipped and depilated dorsal skin produced the desired depth of injury. This model is applicable for the study of the three main components of the burn wound healing process: epithelialization, contraction and scar formation. It is recommended that the India ink injection technique be used to confirm the depth of the burn wound.
本文描述了一种可重复的深度部分皮肤厚度烧伤模型,该模型使用豚鼠来研究这种损伤的愈合过程。将圆形铝模板加热至75摄氏度,并应用于湿润、剪毛和脱毛的背部皮肤5秒钟,可产生所需的损伤深度。该模型适用于研究烧伤创面愈合过程的三个主要组成部分:上皮化、收缩和瘢痕形成。建议使用印度墨水注射技术来确认烧伤创面的深度。