Department of Surgery, University of California San Francisco, 513 Parnassus Avenue, S321, San Francisco, CA 94143, USA.
World J Surg. 2013 Mar;37(3):498-503. doi: 10.1007/s00268-012-1864-x.
Surgical conditions represent an immense yet underrecognized source of disease burden globally. Characterizing the burden of surgical disease has been defined as a priority research agenda in global surgery. Little is known about the epidemiology of inguinal hernia, a common easily treatable surgical condition, in resource-poor settings.
Using data from the National Health and Nutrition Examination Survey prospective cohort study of inguinal hernia, we created a method to estimate hernia epidemiology in Ghana. We calculated inguinal hernia incidence and prevalence using Ghanaian demographic data and projected hernia prevalence under three surgical rate and hernia incidence scenarios. Disability adjusted life-years (DALYs) associated with inguinal hernia along with costs for surgical repair were estimated.
According to this approach, the prevalence of inguinal hernia in the Ghanaian general population is 3.15% (range 2.79-3.50%). Symptomatic hernias number 530,082 (range 469,501-588,980). The annual incidence of symptomatic hernias is 210 (range 186-233) per 100,000 population. At the estimated Ghanaian hernia repair rate of 30 per 100,000, a backlog of 1 million hernias in need of repair develop over 10 years. The cost of repairing all symptomatic hernias in Ghana is estimated at US $53 million, and US $106 million would be required to eliminate hernias over a 10-year period. Nearly 5 million DALYs would be averted with the repair of prevalent cases of symptomatic hernia in Ghana.
Data generated by our method indicate the extent to which Ghana lacks the surgical capacity to address its significant inguinal hernia disease burden. This approach provides a simple framework for calculating inguinal hernia epidemiology in resource-poor settings that may be used for advocacy and program planning in multiple country contexts.
手术条件是全球范围内巨大但尚未被充分认识的疾病负担来源。全球外科领域已经将描述手术疾病负担定义为优先研究议程。在资源匮乏的环境中,关于腹股沟疝这一常见且易于治疗的外科疾病的流行病学情况,人们知之甚少。
我们利用来自全国健康和营养检查调查前瞻性队列研究中腹股沟疝的数据,创建了一种在加纳估算疝流行病学的方法。我们使用加纳人口数据计算了腹股沟疝的发病率和患病率,并根据三种手术率和疝发病率情景预测了疝的患病率。还估算了与腹股沟疝相关的残疾调整生命年(DALY)以及手术修复的费用。
根据这种方法,加纳普通人群中腹股沟疝的患病率为 3.15%(范围 2.79%-3.50%)。有症状的疝患者数量为 530082 例(范围 469501-588980)。每年有症状的疝发病率为 210 例(范围 186-233)/10 万人。按照加纳估计的疝修复率 30/10 万人,在 10 年内会有 100 万例需要修复的疝积压。在加纳修复所有有症状的疝的费用估计为 5300 万美元,要在 10 年内消除疝需要花费 1.06 亿美元。通过修复加纳流行的有症状疝病例,将近可避免 500 万残疾调整生命年。
我们的方法生成的数据表明,加纳缺乏解决其巨大的腹股沟疝疾病负担的手术能力。这种方法为在资源匮乏的环境中计算腹股沟疝流行病学提供了一个简单的框架,可用于多个国家背景下的宣传和规划项目。