韩国幼儿卡介苗接种的现状
The Current Status of BCG Vaccination in Young Children in South Korea.
作者信息
Lee Hyejon, Dockrell Hazel M, Kim Deok Ryun, Floyd Sian, Oh Sue Yeon, Lee Jin Bum, Kim Hee Jin
机构信息
Translational Research Division, International Vaccine Institute, Seoul, Korea. ; Department of Technical Cooperation, Korean Institute of Tuberculosis, Seoul, Korea. ; Department of Microbiology, Institute of Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Korea.
出版信息
Tuberc Respir Dis (Seoul). 2012 Apr;72(4):374-80. doi: 10.4046/trd.2012.72.4.374. Epub 2012 Apr 30.
BACKGROUND
Delivery of Bacille Calmette-Guréin (BCG) Tokyo vaccine, with the multipuncture device, has been much preferred over BCG Pasteur, with the intradermal method, possibly due to the easier manner of administration, a desire to avoid any trouble with scars, as well as side effects and higher profits to providers in South Korea.
METHODS
To determine BCG scar status in 0~6 year old children vaccinated with two BCG vaccines (Pasteur BCG vaccine with intradermal method and BCG Tokyo vaccine with percutaneous method), the data from the national BCG scar survey in 2006 was analyzed.
RESULTS
Based on the national survey, the high proportion that were vaccinated with BCG Tokyo vaccines with the multipuncture method (64.5%) was noted in 06 year old Korean children. From inspection of scar formation, as an indicator of vaccination, the median number of the visible pin scars from the percutaneous method was 16 (interquartile range, 1218) in the Korean children, and pin scars decreased as the age of the children increased (p<0.001).
CONCLUSION
The findings in this survey clearly showed a growing preference of parents for the BCG Tokyo vaccines by the multipuncture method in South Korea.
背景
在韩国，使用多针刺接种装置接种东京卡介苗（BCG）比采用皮内注射法接种巴斯德卡介苗更受青睐，这可能是由于其接种方式更简便、人们希望避免疤痕问题以及副作用，同时对提供者来说利润更高。
方法
为确定接种两种卡介苗（采用皮内注射法的巴斯德卡介苗和采用经皮接种法的东京卡介苗）的0至6岁儿童的卡介苗疤痕状况，对2006年全国卡介苗疤痕调查的数据进行了分析。
结果
基于全国调查，发现0至6岁韩国儿童中采用多针刺法接种东京卡介苗的比例较高（64.5%）。通过检查作为疫苗接种指标的疤痕形成情况，韩国儿童经皮接种法可见针痕的中位数为16（四分位间距，12至18），且针痕数量随儿童年龄增长而减少（p<0.001）。
结论
本次调查结果清楚地表明，在韩国，家长越来越倾向于采用多针刺法接种东京卡介苗。
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