Tresadern J C, Asbury D, Hartley G, Sellwood R A, Borg-Grech A, Watson R J
University Department of Surgery, Withington Hospital, Manchester, UK.
Br J Surg. 1990 Mar;77(3):320-2. doi: 10.1002/bjs.1800770327.
We have undertaken fine-wire localization and biopsy of 130 impalpable breast lesions identified by mammography and considered suspicious of malignancy. Histologically 22 of these lesions were invasive carcinomas and 24 were in situ carcinomas (35 per cent malignant). Twenty-nine per cent of the lesions were identified during the screening of asymptomatic women. In the remainder, the presenting symptoms bore no relation to the eventual histological diagnosis. Clusters of microcalcification were more often malignant than were abnormal soft-tissue masses. Malignancy in the absence of microcalcification was almost always invasive.
我们对130例通过乳房X线摄影检查发现且怀疑为恶性的不可触及乳腺病变进行了细针定位和活检。组织学检查显示，这些病变中有22例为浸润性癌，24例为原位癌（恶性率为35%）。29%的病变是在对无症状女性进行筛查时发现的。其余病例中，出现的症状与最终的组织学诊断无关。微钙化簇比异常软组织肿块更常为恶性。无微钙化的恶性病变几乎均为浸润性。
