Department of Medicine, Institute of Health Policy Management and Evaluation, Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada.
Transfusion. 2013 Aug;53(8):1688-97; quiz 1687. doi: 10.1111/trf.12007. Epub 2012 Dec 11.
Anemia is one of the most common complications of coronary artery bypass graft (CABG) surgery and has been shown to be associated with increased morbidity and mortality. The impact of anemia on hospital readmission after CABG, a potential measure of delayed complications, has not been addressed.
We conducted a single-center retrospective study of 2102 patients who had CABG in Ontario to determine whether anemia at hospital discharge was associated with increased 30-day hospital readmissions, readmission secondary to cardiac disease, and 30-day mortality using administrative data.
Of the 2102 patients, 224 patients (11%) were readmitted within 30 days of hospital discharge. Infection was the leading cause of readmissions (24%), followed by heart failure (13%), pulmonary disease (7%), and hemorrhagic disease (7%). Overall, 2.6% of patients were readmitted because of cardiac disease. Of patients discharged, 48% were discharged with a hemoglobin (Hb) level between 8 and 10 g/dL and 42% between 10 and 12 g/dL. Predischarge Hb concentration was not a significant independent predictor of 30-day readmission to the hospital due to all causes, readmission to the hospital due to cardiac causes, or 30-day mortality. A higher comorbidity score, adjusted odds ratio (OR) of 2.1 (95% confidence interval [CI], 1.3-3.6), leg and sternal wound infections OR of 1.9 (95% CI, 1.2-3.0), and postoperative renal failure OR of 1.4 (95% CI, 1.2-2.0) were associated with increased 30-day readmission rates.
The predischarge Hb concentration after CABG was not associated with 30-day readmissions.
贫血是冠状动脉旁路移植术(CABG)术后最常见的并发症之一,已被证明与发病率和死亡率增加有关。贫血对 CABG 后住院再入院的影响(延迟并发症的潜在衡量标准)尚未得到解决。
我们对在安大略省进行 CABG 的 2102 例患者进行了单中心回顾性研究,以确定出院时的贫血是否与 30 天内的住院再入院、因心脏疾病而再次入院以及使用行政数据确定的 30 天死亡率增加相关。
在 2102 例患者中,有 224 例(11%)在出院后 30 天内再次住院。感染是再入院的主要原因(24%),其次是心力衰竭(13%)、肺部疾病(7%)和出血性疾病(7%)。总体而言,有 2.6%的患者因心脏疾病再次入院。出院患者中,48%的血红蛋白(Hb)水平在 8 至 10g/dL 之间,42%的 Hb 水平在 10 至 12g/dL 之间。出院前 Hb 浓度并不是所有原因导致的 30 天内再次住院、因心脏原因导致的再次住院或 30 天死亡率的显著独立预测因素。较高的合并症评分(调整后的比值比 [OR]为 2.1[95%置信区间[CI],1.3-3.6])、腿部和胸骨伤口感染(OR 为 1.9[95%CI,1.2-3.0])和术后肾衰竭(OR 为 1.4[95%CI,1.2-2.0])与 30 天内再入院率增加相关。
CABG 后出院前 Hb 浓度与 30 天内再入院无关。