Manji Rizwan A, Arora Rakesh C, Singal Rohit K, Hiebert Brett M, Menkis Alan H
Department of Surgery, University of Manitoba and Cardiac Sciences Program, Winnipeg, MB, Canada
Department of Surgery, University of Manitoba and Cardiac Sciences Program, Winnipeg, MB, Canada.
J Am Heart Assoc. 2017 Feb 7;6(2):e004072. doi: 10.1161/JAHA.116.004072.
Prolonged intensive care unit length of stay (prICULOS) following cardiac surgery (CS) in older adults is increasingly common but rehospitalization characteristics and outcomes are understudied. We sought to describe the rehospitalization characteristics and subsequent non-institutionalized survival of prICULOS (ICULOS ≥5 days) patients and identify modifiable risk factors to decrease 30-day rehospitalization.
Consecutive patients from January 1, 2000 to December 31, 2011 were analyzed utilizing linked clinical and administrative databases. Logistic regression was used to identify risk factors associated with 30-day rehospitalization. Out of 9210 consecutive patients discharged from the hospital alive, 596 (6.5%) experienced prICULOS. Cumulative incidence of rehospitalization for the prICULOS cohort at 30 and 365 days was 17.5% and 45.6% versus 11.4% and 28.1% for non-prICULOS (P<0.01). Over 40% of rehospitalizations for the entire cohort occurred within 30 days of discharge costing over $12 million. The most common reasons for rehospitalization were heart failure (in prICULOS) and infection (in non-prICULOS). Rehospitalization within 30 days was associated with a 2.29-fold risk of poor 1-year noninstitutionalized survival for the entire cohort. Potentially modifiable factors affecting 30-day rehospitalization included lack of physician visits within 30 days of discharge (odds ratio 2.11; P=0.01), and preoperative anxiety diagnosis (odds ratio 2.20; P=0.01).
PrICULOS patients have high rates of rehospitalization that is associated with an increased rate of poor noninstitutionalized survival. Addressing modifiable risk factors including early postdischarge access to physician services, as well as access to mental health services may improve patient outcomes.
老年患者心脏手术后在重症监护病房的住院时间延长(prICULOS,即重症监护病房住院时间≥5天)日益常见,但再住院特征和结局尚未得到充分研究。我们试图描述prICULOS患者的再住院特征及随后的非机构化生存情况,并确定可改变的风险因素以降低30天再住院率。
利用关联的临床和管理数据库对2000年1月1日至2011年12月31日期间的连续患者进行分析。采用逻辑回归确定与30天再住院相关的风险因素。在9210例连续出院存活的患者中,596例(6.5%)经历了prICULOS。prICULOS队列在30天和365天的再住院累积发生率分别为17.5%和45.6%,而非prICULOS队列分别为11.4%和28.1%(P<0.01)。整个队列超过40%的再住院发生在出院后30天内,费用超过1200万美元。再住院的最常见原因是心力衰竭(prICULOS患者中)和感染(非prICULOS患者中)。整个队列中,30天内再住院与1年非机构化生存不良风险增加2.29倍相关。影响30天再住院的潜在可改变因素包括出院后30天内无医生问诊(比值比2.11;P=0.01)以及术前焦虑诊断(比值比2.20;P=0.01)。
PrICULOS患者再住院率高,且与非机构化生存不良率增加相关。解决可改变的风险因素,包括出院后早期获得医生服务以及获得心理健康服务,可能会改善患者结局。