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[前列腺癌近距离放射治疗的发展]

[Evolution of prostate cancer brachytherapy].

作者信息

Hannoun-Levi Jean-Michel, Chevallier Daniel, Cosset Jean-Marc, Gerbaulet Alain

机构信息

Département de radiothérapie, Université Nice-Sophia, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice Cedex, France.

出版信息

Bull Cancer. 2012 Dec;99(12):1175-81. doi: 10.1684/bdc.2012.1668.

Abstract

Curietherapy, more commonly named brachytherapy, is one of the oldest irradiation techniques used for prostate cancer. Prostate brachytherapy evolved according to the scientific and technological progress. After a historical reminder of the evolution of prostate brachytherapy, different technical aspects are discussed: low-dose rate brachytherapy using permanent or temporary implants, high-dose rate brachytherapy as well as new imaging modalities. Prostate brachytherapy indications are listed regarding to the evidence-based medicine data for low, intermediate and high risks prostate cancers. Potential indications and new research programs (focal therapy, high-dose rate, single-dose brachytherapy) are also presented.

摘要

居里疗法,更常见的名称是近距离放射疗法,是用于前列腺癌的最古老的放射技术之一。前列腺近距离放射疗法随着科技进步而发展。在对前列腺近距离放射疗法的发展进行历史回顾之后,讨论了不同的技术方面:使用永久性或临时性植入物的低剂量率近距离放射疗法、高剂量率近距离放射疗法以及新的成像模式。根据低、中、高风险前列腺癌的循证医学数据列出了前列腺近距离放射疗法的适应症。还介绍了潜在适应症和新的研究项目(聚焦治疗、高剂量率、单剂量近距离放射疗法)。

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