Department of Psychology, Stellenbosch University, Private Bag X1Matieland, Stellenbosch, 7602, South Africa.
AIDS Behav. 2013 Jan;17(1):319-28. doi: 10.1007/s10461-012-0374-z.
In addition to personal and psychological factors, structural factors may reduce the likelihood of optimal adherence to antiretroviral therapy (ART) among persons living with HIV. In this mixed-method study we report on the development of a scale to assess the salience of various structural barriers to ART adherence. After following conventional guidelines for scale development, two scales measuring structural barriers to adherence to clinic attendance and pill-taking were administered to 291 patients receiving ART at a public hospital in South Africa. Both exploratory and higher order factor analysis indicated that a single underlying general factor was appropriate for both scales. The final scales consisted of 12 items for the structural barriers to clinic attendance scale and 13 items for the structural barriers to medication-taking scale. Both scales displayed excellent internal consistency with Cronbach alpha coefficients above 0.80. Research to determine the construct validity of the scales may be a next step in this line of research.
除了个人和心理因素外，结构因素也可能降低艾滋病毒感染者接受抗逆转录病毒治疗（ART）的最佳依从性。在这项混合方法研究中，我们报告了一种评估各种与 ART 依从性相关的结构障碍重要性的量表的开发情况。在遵循量表开发常规指南后，对在南非一家公立医院接受 ART 治疗的 291 名患者进行了评估就诊和服药依从性结构障碍的两个量表的测试。探索性和高阶因子分析均表明，对于这两个量表，单一的潜在通用因子是合适的。最终的量表由就诊依从性结构障碍量表的 12 个项目和服药依从性结构障碍量表的 13 个项目组成。这两个量表的内部一致性都非常好，克朗巴赫 α 系数均高于 0.80。下一步的研究可能是确定这些量表的结构效度。
