Zhou X
Zhonghua Liu Xing Bing Xue Za Zhi. 1990 Feb;11(1):5-8.
Seventy-five cases of coronary heart disease with gallstones and another 75 cases without gallstones as controls were studied. The positive rates of previous cholecystitis and chronic intestinal diseases, and familial history of gallstone in the first group were obviously higher than those in the control group (P less than 0.05 & 0.11). The odd ratio (OR) was 4.22, 9.00 and 6.00, respectively. There was no difference in high serous lipid level, obesity, high cholesterol and fat intake (P greater than 0.05) neither group took clofirrate. It demonstrated that susceptible factors for coronary heart disease patients to develop gallstones are probably the same as in general population. The imbalance of lipoid metabolism had no direct associate with gallstones. The synergistic action of the imbalance of lipid metabolism and administration of some kinds of medicine might be a susceptible factor for coronary heart disease patients to develop gallstones.
研究了75例冠心病合并胆结石患者，并以另外75例无胆结石患者作为对照。第一组既往胆囊炎和慢性肠道疾病的阳性率以及胆结石家族史明显高于对照组（P<0.05和0.11）。优势比（OR）分别为4.22、9.00和6.00。两组在高血清脂质水平、肥胖、高胆固醇和脂肪摄入方面无差异（P>0.05），两组均未服用氯贝丁酯。结果表明，冠心病患者发生胆结石的易感因素可能与一般人群相同。脂质代谢失衡与胆结石无直接关联。脂质代谢失衡与某些药物的联合作用可能是冠心病患者发生胆结石的易感因素。
