School of Pharmacy, Virginia Commonwealth University, Richmond, 23298-0533, USA.
J Am Pharm Assoc (2003). 2012;52(6):e144-52. doi: 10.1331/JAPhA.2012.11258.
To determine the impact of telephone medication therapy management (MTM) on medication- and health-related problems (MHRPs), medication adherence, and total drug costs for Medicare Part D participants.
Quasiexperimental.
Regional Medicare Part D plan in Texas in 2007.
Medicare Part D beneficiaries who were MTM eligible.
Pharmacist-provided telephone MTM consultation.
Change in MHRPs, medication adherence, and total drug costs from baseline to 12-month follow-up.
The intervention (n = 60) and control (n = 60) groups were similar in age (71.2 ± 7.5 years and 73.9 ± 8.0 years [mean ± SD], respectively), number of medications (13.0 ± 3.2 and 13.2 ± 3.4), chronic diseases (6.5 ± 2.3 and 7.0 ± 2.1), and medication regimen complexity index (21.5 ± 7.8 and 22.8 ± 6.9). Men made up 51% of the intervention group and 28% of the control group ( P = 0.009). MHRPs at baseline were 4.8 ± 2.7 in the intervention group and 9.2 ± 2.9 in the control group, with 2.2 ± 2.0 and 7.3 ± 3.0 at the 12-month follow-up. MHRPs decreased ( P = 0.01) in the intervention group. We found no predictors of change in medication adherence. Drug costs decreased by $682 ± 2,141 in the intervention group and increased by $119 ± 1,763 in the control group. A t test indicated that the cost difference was significant ( P = 0.03), but the adjusted regression analysis did not identify any significant predictors.
A telephone MTM program reduced MHRPs. Unadjusted cost comparisons showed cost savings in the intervention group. Future research should focus on understanding how telephone MTM affects medication adherence.
确定电话药物治疗管理(MTM)对医疗保险处方药计划参与者的药物和健康相关问题(MHRP)、药物依从性和总药物费用的影响。
准实验。
2007 年德克萨斯州的医疗保险处方药计划的区域计划。
符合 MTM 条件的医疗保险处方药计划参与者。
药剂师提供的电话 MTM 咨询。
从基线到 12 个月随访时 MHRP、药物依从性和总药物费用的变化。
干预组(n=60)和对照组(n=60)在年龄(分别为 71.2±7.5 岁和 73.9±8.0 岁[均值±标准差])、药物数量(分别为 13.0±3.2 和 13.2±3.4)、慢性病(分别为 6.5±2.3 和 7.0±2.1)和药物方案复杂性指数(分别为 21.5±7.8 和 22.8±6.9)方面相似。男性在干预组和对照组中分别占 51%和 28%(P=0.009)。干预组在基线时的 MHRP 为 4.8±2.7,对照组为 9.2±2.9,在 12 个月随访时分别为 2.2±2.0 和 7.3±3.0。干预组的 MHRP 减少(P=0.01)。我们没有发现药物依从性变化的预测因素。干预组的药物费用减少了 682±2141 美元,对照组增加了 119±1763 美元。t 检验表明成本差异具有统计学意义(P=0.03),但调整后的回归分析未发现任何显著的预测因素。
电话 MTM 项目减少了 MHRP。未经调整的成本比较显示,干预组有成本节约。未来的研究应重点关注了解电话 MTM 如何影响药物依从性。