Gupta Rijuneeta, Yadav Jagveer Singh, Yadav Shilpa, Wadood Abdul
Department of Otolaryngology and Head & Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Orbit. 2012 Dec;31(6):441-5. doi: 10.3109/01676830.2012.711886.
Burkitt's lymphoma (BL) is a rare monoclonal proliferation of Blymphocytes and is classified as a poorly differentiated lymphocytic lymphoma. Typically, Burkitt's lymphoma involves the jaw bones, but the orbit can also be involved. Burkitt"s lymphoma is seen, sporadically in India, and 3 cases of orbital Burkitt's lymphoma were diagnosed during the past 4 years. Three cases of acute proptosis in children are presented to us. The provisional clinical diagnosis was rhabdomyosarcoma and the histopathology revealed Burkitt's lymphoma. The fast growth rate, hematologic manifestations and the urgency of diagnosis are emphasized. We present 3 cases here and review prevailing concepts about Burkitt's lymphoma.
伯基特淋巴瘤(BL)是B淋巴细胞的一种罕见单克隆增殖性疾病,被归类为低分化淋巴细胞淋巴瘤。通常,伯基特淋巴瘤累及颌骨,但眼眶也可受累。在印度偶见伯基特淋巴瘤,过去4年中诊断出3例眼眶伯基特淋巴瘤。本文报告3例儿童急性眼球突出病例。初步临床诊断为横纹肌肉瘤,组织病理学检查显示为伯基特淋巴瘤。强调了其快速生长速度、血液学表现及诊断的紧迫性。我们在此呈现3例病例,并综述关于伯基特淋巴瘤的主流观点。