Chambers H G, Silver S M, Bucknell A L
Orthopaedic Surgery Service, Brooke Army Medical Center, Fort Sam Houston, Texas 78234.
Clin Orthop Relat Res. 1990 May(254):255-60.
Patient-controlled analgesia (PCA) is a concept that permits patients to administer a prescribed dose of narcotic to themselves when they experience pain. Six patients developed colonic pseudoobstruction after the use of morphine sulfate administered via a PCA infuser. Early recognition and prompt treatment make this a transient, reversible illness. Treatment includes discontinuing the use of the PCA morphine, eliminating oral intake, ensuring adequate hydration and electrolyte balance, placing a nasogastric tube, rolling the patient, and closely observing for signs and symptoms of worsening colonic distention and possible rupture.
患者自控镇痛（PCA）是一种允许患者在感到疼痛时自行给予规定剂量麻醉剂的概念。6名患者在通过PCA输注器使用硫酸吗啡后出现结肠假性梗阻。早期识别和及时治疗使这成为一种短暂的、可逆的疾病。治疗包括停止使用PCA吗啡、停止经口摄入、确保充足的水合作用和电解质平衡、放置鼻胃管、翻动患者，并密切观察结肠扩张加重和可能破裂的体征和症状。
