Erickson Mark A, Morrato Elaine H, Campagna Elizabeth J, Elise Benefield, Miller Nancy H, Kempe Allison
Department of Orthopedic Surgery, Children's Hospital Colorado, CO 80045, USA.
J Pediatr Orthop. 2013 Jan;33(1):80-90. doi: 10.1097/BPO.0b013e318269c537.
We performed a retrospective cohort study of 7637 spinal fusion surgical cases from 2004 to 2006 at 38 children's hospitals participating in the Pediatric Health Information System database to evaluate the variability of in-hospital outcomes by patient factors and between facilities in children who underwent spinal surgery.
Outcomes were stratified by whether children did or did not have neurological impairment. Multilevel multivariate logistic regression models were used to determine patient and hospital factors associated with in-hospital infections, surgical complications, and length of stay (LOS)≥10 days.
Neurologically impaired (NI) children (N=2117 out of 7637) represented 28% of the cases. The interhospital interquartile range of LOS for NI children was 6 to 8 days (median 7 d) and for non-neurologically impaired (NNI) children was 5 to 6 days (median 5 d). Children with NI had roughly 6 times higher rates of in-hospital infection and 3 times higher complication rates: major interhospital variation was seen for both of these outcomes. Hospital rates of infection ranged from 0% to 27% (median 10%) for NI and from 0% to 14% (median 2%) for NNI children. Complication rates ranged from 0% to 89% (median 33%) for NI and from 3% to 68% (median 9%) for NNI children. The following factors were associated with a LOS≥10 days: in-hospital infection (P<0.0001), surgical complication (P<0.0001), and anterior/posterior versus posterior-only surgery (P<0.0001). Hospital case volume was not associated with infection, surgical complication, or LOS≥10 days.
Substantial variation exists in reported outcomes for children undergoing spinal surgery in children's hospitals within the United States. Further study is needed to characterize hospital-level factors related to surgical outcome to direct future quality improvement.
我们对参与儿科健康信息系统数据库的38家儿童医院在2004年至2006年期间的7637例脊柱融合手术病例进行了一项回顾性队列研究,以评估患者因素和接受脊柱手术儿童的不同医疗机构之间住院结局的差异。
根据儿童是否有神经功能损害对结局进行分层。使用多水平多变量逻辑回归模型来确定与医院感染、手术并发症以及住院时间(LOS)≥10天相关的患者和医院因素。
神经功能受损(NI)儿童(7637例中的2117例)占病例的28%。NI儿童住院时间的医院间四分位距为6至8天(中位数7天),非神经功能受损(NNI)儿童为5至6天(中位数5天)。NI儿童的医院感染率大约高6倍,并发症发生率高3倍:这两种结局均存在较大的医院间差异。NI儿童的医院感染率在0%至27%之间(中位数10%),NNI儿童在0%至14%之间(中位数2%)。并发症发生率NI儿童在0%至89%之间(中位数33%),NNI儿童在3%至68%之间(中位数9%)。以下因素与住院时间≥10天相关:医院感染(P<0.0001)、手术并发症(P<0.0001)以及前路/后路与单纯后路手术(P<0.0001)。医院病例数量与感染、手术并发症或住院时间≥10天无关。
在美国儿童医院接受脊柱手术的儿童所报告的结局存在很大差异。需要进一步研究以确定与手术结局相关的医院层面因素,从而指导未来的质量改进。