[Influence of glutaraldehyde on Na+, K+-ATPase activity of brain tissue and enzymic preparations under conditions of electron cytochemical analysis].

The glutaraldehyde inhibitory influence on Mg2+, Na+, K+-ATPase activity of the brain tissue is shown to increase with a rise in the glutaraldehyde concentration; a direct dependence is established between the degree of inhibition and the treatment time and temperature. The glutaraldehyde inhibitory effect on the activity of the brain microsomal fraction Na+, K+-ATPase preparations under the same treatment conditions is considerably higher. A histochemical detection of the cerebral cortex Mg2+, Na+, K+-ATPase was carried out under optimal conditions of fixation, and a conclusion is made on possibility of using glutaraldehyde as a fixator in histochemical investigations.