Nazarenko V I, Chomutovskiĭ O A, Didyk O A
Ukr Biokhim Zh (1978). 1979 Nov-Dec;51(6):659-64.
The glutaraldehyde inhibitory influence on Mg2+, Na+, K+-ATPase activity of the brain tissue is shown to increase with a rise in the glutaraldehyde concentration; a direct dependence is established between the degree of inhibition and the treatment time and temperature. The glutaraldehyde inhibitory effect on the activity of the brain microsomal fraction Na+, K+-ATPase preparations under the same treatment conditions is considerably higher. A histochemical detection of the cerebral cortex Mg2+, Na+, K+-ATPase was carried out under optimal conditions of fixation, and a conclusion is made on possibility of using glutaraldehyde as a fixator in histochemical investigations.
