Li Wenjuan, Xu Yi, Fan Qi, Cao Kun, Zhang Qing, Wang Changrui, Qian Wei, Zhang Xiaofeng
Chemistry and Chemical Engineering College, Chongqing University, Chongqing 400030, China.
Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(16):2492-7.
With the constant development of the drug screening technology, new screening methods and techniques have came to the fore, driving drug screening to grow rapidly and efficiently with a high throughput. Characterized by micro-scale analysis, high throughput, inheritability and good biocompatibility, the micro-fluidic analytical technology provides a new method and technical platform for screening active ingredients from natural products. This essay introduces multiple methods used for screening active ingredients from natural products and focuses on the micro-fluidic chip screening technology combined with cell culture and its characteristics, the composition of the platform of the micro-fluidic chip screening technology and its application in screening active ingredients from natural products.