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Generation of superoxide anion and hydrogen peroxide induced by nifurtimox in Trypanosoma cruzi.

作者信息

Docampo R, Stoppani A O

出版信息

Arch Biochem Biophys. 1979 Oct 1;197(1):317-21. doi: 10.1016/0003-9861(79)90251-0.

DOI:10.1016/0003-9861(79)90251-0
PMID:232403
Abstract
摘要

相似文献

1
Generation of superoxide anion and hydrogen peroxide induced by nifurtimox in Trypanosoma cruzi.
Arch Biochem Biophys. 1979 Oct 1;197(1):317-21. doi: 10.1016/0003-9861(79)90251-0.
2
[Undesirable effects of benznidazole and nifurtimox].[苯硝唑和硝呋替莫的不良作用]
Medicina (B Aires). 1983;43(3):291-5.
3
Mechanism of nifurtimox toxicity in different forms of Trypanosoma cruzi.硝呋替莫对不同形式克氏锥虫的毒性机制。
Biochem Pharmacol. 1981 Jul 15;30(14):1947-51. doi: 10.1016/0006-2952(81)90204-5.
4
[Mechanism of the trypanocidal action of nifurtimox and other nitro-derivatives on Trypanosoma cruzi].[硝呋替莫及其他硝基衍生物对克氏锥虫的杀锥虫作用机制]
Medicina (B Aires). 1980;40 Suppl 1:10-6.
5
Lipid alterations induced by nifurtimox in Trypanosoma cruzi.
Mol Biochem Parasitol. 1986 Dec;21(3):221-6. doi: 10.1016/0166-6851(86)90127-1.
6
Nitrofuran enhancement of microsomal electron transport, superoxide anion production and lipid peroxidation.呋喃妥因对微粒体电子传递、超氧阴离子生成及脂质过氧化的增强作用。
Arch Biochem Biophys. 1981 Apr 1;207(2):316-24. doi: 10.1016/0003-9861(81)90039-4.
7
Activity against Trypanosoma cruzi of new analogues of nifurtimox.
Arch Pharm (Weinheim). 1987 Feb;320(2):115-20. doi: 10.1002/ardp.19873200205.
8
Trypanosoma cruzi: nifurtimox's effect on infectivity.
Exp Parasitol. 1977 Dec;43(2):370-5. doi: 10.1016/0014-4894(77)90042-x.
9
[Effects of nifurtimox, benznidazole, and beta-lapachone on the metabolism of DNA, RNA and proteins in Trypanosoma cruzi].[硝呋替莫、苯硝唑和β-拉帕醌对克氏锥虫DNA、RNA和蛋白质代谢的影响]
Rev Argent Microbiol. 1983;15(4):193-204.
10
Photosensitization by the trypanocidal agent crystal violet. Type I versus type II reactions.
Chem Biol Interact. 1986 May;58(2):161-72. doi: 10.1016/s0009-2797(86)80095-3.

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Mitochondrial Peroxiredoxin Promotes Infectivity in Macrophages and Attenuates Nifurtimox Toxicity.
线粒体过氧化物酶促进巨噬细胞感染性并减轻硝呋替莫毒性。
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Nifurtimox Is Effective Against Neural Tumor Cells and Is Synergistic with Buthionine Sulfoximine.硝呋替莫对神经肿瘤细胞有效且与丁硫氨酸亚砜胺具有协同作用。
Sci Rep. 2016 Jun 10;6:27458. doi: 10.1038/srep27458.
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Microbiol Mol Biol Rev. 2014 Mar;78(1):40-73. doi: 10.1128/MMBR.00045-13.
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Evaluating 5-nitrofurans as trypanocidal agents.评估 5-硝基呋喃类化合物作为杀锥虫剂。
Antimicrob Agents Chemother. 2013 Apr;57(4):1638-47. doi: 10.1128/AAC.02046-12. Epub 2013 Jan 18.
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Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma brucei.非靶向代谢组学揭示硝呋替莫和依氟鸟氨酸联用对布氏锥虫无协同作用。
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Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design.锥虫硫醇还原酶：抗锥虫和抗利什曼原虫药物设计的一个可行化疗靶点。
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