Department of Veterinary Medicine, Queen's Veterinary School Hospital, University of Cambridge, Cambridge, UK.
Vet Comp Oncol. 2014 Dec;12(4):287-98. doi: 10.1111/vco.12012. Epub 2012 Dec 13.
Current staging of canine mast cell tumours (MCTs) practiced by many veterinarians involves a minimum of lymph node (LN) assessment, abdominal ultrasound and thoracic radiography. Historically, some have advocated buffy coat and bone marrow evaluation. Two hundred and twenty dogs with MCT seen at a referral clinic were staged using LN palpation/cytology, thoracic radiography and abdominal ultrasound. The utility of each method was evaluated by considering prevalence of spread and future behaviour. At presentation, 30.9% of dogs had metastases to the local LN; 6.8% of all the dogs also had distant metastases. No dog had or developed distant metastasis in the absence of LN metastasis. No dog had convincing evidence of pulmonary metastasis. In this series, the local LN was sentinel to metastasis and in the absence of local LN metastasis, the utility of further staging was low. Thoracic radiography was not useful in the staging of canine MCT.
当前,许多兽医对犬肥大细胞瘤(MCT)的分期评估最少涉及淋巴结(LN)评估、腹部超声和胸部放射摄影。从历史上看,一些人主张进行血涂片和骨髓评估。在一家转诊诊所就诊的 220 只患有 MCT 的狗使用 LN 触诊/细胞学、胸部放射摄影和腹部超声进行分期。通过考虑扩散的普遍性和未来的行为,评估了每种方法的效用。在就诊时,30.9%的狗出现局部 LN 转移;所有狗中有 6.8%还存在远处转移。没有狗在没有 LN 转移的情况下发生或发展为远处转移。没有狗有确凿的证据表明存在肺转移。在本系列中,局部 LN 是转移的前哨,在没有局部 LN 转移的情况下,进一步分期的效用较低。胸部放射摄影在犬肥大细胞瘤的分期中没有用处。