Gayer M L, Henry-Suchet J
Unité de contrôle des naissances et Traitement de l'infertilité, Hôpital Saint-Louis, Paris.
J Gynecol Obstet Biol Reprod (Paris). 1990;19(2):155-64.
A series of 89 caucasian women, who had been operated on for non-infectious tubal infertility were studied to find out what contraceptive methods they had used before they became infertile (oral contraception, intra-uterine contraceptive device and other methods). A matched series of 178 fertile women were used as a control group. The numbers who had chlamydia were studied as a function of the method of contraception in the group of infertile women. This work shows that women with tubal infertility due originally to infection had less often used oral contraception than the matched group of fertile women had. One can conclude that oral contraception acts as a prevention against this cause of infertility. The role played by intra-uterine contraceptive devices is difficult to establish. All the same, there is a significant relationship between the use of intra-uterine devices and tubal infertility of infectious origin, whether we look at multiparae or women between 25 and 34 years of age. This study also shows that chlamydia is not associated with the use of combined preparation oral contraceptives, nor with the use of the intra-uterine device in women who have tubal factor infertility. This study all the same shows that it does seem to be important to advise oral contraception in preference to the intra-uterine device in women who are still wanting to have a pregnancy, even if they are multiparae or multigravidae.
对89名因非感染性输卵管因素导致不孕而接受手术的白人女性进行了一项研究,以了解她们在不孕之前使用过哪些避孕方法(口服避孕药、宫内节育器及其他方法)。选取178名有生育能力的女性作为匹配对照组。研究了不孕女性组中感染衣原体的人数与避孕方法之间的关系。这项研究表明,最初因感染导致输卵管不孕的女性使用口服避孕药的频率低于匹配的有生育能力女性组。由此可以得出结论,口服避孕药可预防这种不孕原因。宫内节育器所起的作用难以确定。尽管如此,无论观察经产妇还是25至34岁的女性,使用宫内节育器与感染性输卵管不孕之间都存在显著关联。这项研究还表明,衣原体感染与使用复方口服避孕药无关,也与输卵管因素不孕女性使用宫内节育器无关。即便如此,这项研究表明,对于仍希望怀孕的女性,即使她们是经产妇或多产妇,建议优先使用口服避孕药而非宫内节育器似乎很重要。