Adams Simon Timothy, Salhab Mohamed, Hussain Zeiad Ihsan, Miller Glenn V, Leveson Stephen H
Department of General Surgery, York Hospital, Wigginton Road, York YO318HE, UK.
Blood Press. 2013 Jun;22(3):131-7. doi: 10.3109/08037051.2012.749570. Epub 2012 Dec 18.
It is well established that hypertension and obesity appear to be associated. The exact mechanism by which they are linked is unclear and remains a topic of a great deal of research. Current NICE guidelines recommend that patients with a BMI in excess of 35 kg/m(2) should be considered for bariatric surgery if they have a concomitant obesity-associated condition, of which hypertension is one. The commonest bariatric procedure in the UK is the Roux-en-Y gastric bypass, which has been shown to result in long-standing remission of hypertension in up to 93% of patients. This paper summarizes the existing literature on the main theories as to how obesity leads to hypertension as well as the literature concerning the effects of gastric bypass surgery on hypertension.
高血压与肥胖之间似乎存在关联，这一点已得到充分证实。二者之间确切的联系机制尚不清楚，仍是大量研究的主题。英国国家卫生与临床优化研究所（NICE）现行指南建议，体重指数（BMI）超过35kg/m²且伴有肥胖相关疾病（其中高血压是一种）的患者，应考虑接受减肥手术。英国最常见的减肥手术是Roux-en-Y胃旁路术，该手术已被证明能使高达93%的患者长期缓解高血压。本文总结了关于肥胖导致高血压的主要理论的现有文献，以及胃旁路手术对高血压影响的相关文献。
