Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA.
J Addict Dis. 2012;31(4):363-75. doi: 10.1080/10550887.2012.735568.
Research suggests that Attention Deficit Hyperactivity Disorder (ADHD) and nicotine withdrawal symptoms are related; however, it is unknown how this relationship extends across ADHD symptom gradations, differs between inattention and hyperactivity-impulsivity symptom types, and generalizes to a national sample. This study examined cross-sectional associations between childhood ADHD symptom indexes (total, inattention, and hyperactivity-impulsivity) and lifetime DSM-IV nicotine withdrawal symptoms. Results showed that each ADHD symptom index associated with almost every withdrawal symptom (Ps < .01). After controlling for hyperactivity-impulsivity and inattention symptom overlap, inattention (but not hyperactivity-impulsivity) retained incremental associations with most withdrawal symptoms. These findings are relevant for understanding mechanisms of ADHD and smoking comorbidity.
研究表明,注意力缺陷多动障碍(ADHD)和尼古丁戒断症状有关;然而,尚不清楚这种关系如何在 ADHD 症状的不同严重程度中延伸,在注意力不集中和多动冲动症状类型之间有何不同,以及是否适用于全国性样本。本研究考察了儿童期 ADHD 症状指标(总分、注意力不集中和多动冲动)与 DSM-IV 终身尼古丁戒断症状之间的横断面关联。结果表明,每个 ADHD 症状指标都与几乎所有戒断症状相关(P<.01)。在控制了多动冲动和注意力不集中症状的重叠后,注意力不集中(而非多动冲动)与大多数戒断症状仍存在增量关联。这些发现对于理解 ADHD 和吸烟共病的机制具有重要意义。