人类受试者中70 kDa的ζ链相关蛋白（ZAP70）缺乏与胸腺基质细胞异常有关：对T细胞耐受性的影响。 - Suppr

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ζ Chain-associated protein of 70 kDa (ZAP70) deficiency in human subjects is associated with abnormalities of thymic stromal cells: Implications for T-cell tolerance.

作者信息

Poliani Pietro Luigi, Fontana Elena, Roifman Chaim M, Notarangelo Luigi D

出版信息

J Allergy Clin Immunol. 2013 Feb;131(2):597-600.e1-2. doi: 10.1016/j.jaci.2012.11.002. Epub 2012 Dec 14.

DOI:10.1016/j.jaci.2012.11.002

PMID:23245794

Abstract

摘要

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ζ Chain-associated protein of 70 kDa (ZAP70) deficiency in human subjects is associated with abnormalities of thymic stromal cells: Implications for T-cell tolerance.

作者信息

Poliani Pietro Luigi, Fontana Elena, Roifman Chaim M, Notarangelo Luigi D

出版信息

J Allergy Clin Immunol. 2013 Feb;131(2):597-600.e1-2. doi: 10.1016/j.jaci.2012.11.002. Epub 2012 Dec 14.

DOI:10.1016/j.jaci.2012.11.002

PMID:23245794

Abstract

摘要

相似文献

ζ Chain-associated protein of 70 kDa (ZAP70) deficiency in human subjects is associated with abnormalities of thymic stromal cells: Implications for T-cell tolerance.

J Allergy Clin Immunol. 2013 Feb;131(2):597-600.e1-2. doi: 10.1016/j.jaci.2012.11.002. Epub 2012 Dec 14.

A novel Zap70 mutation with reduced protein stability demonstrates the rate-limiting threshold for Zap70 in T-cell receptor signalling.

Immunology. 2014 Mar;141(3):377-87. doi: 10.1111/imm.12199.

Neonatally imprinted stromal cell subsets induce tolerogenic dendritic cells in mesenteric lymph nodes.

Nat Commun. 2018 Sep 25;9(1):3903. doi: 10.1038/s41467-018-06423-7.

Characterization of ζ-associated protein, 70 kd (ZAP70)-deficient human lymphocytes.

J Allergy Clin Immunol. 2010 Dec;126(6):1226-33.e1. doi: 10.1016/j.jaci.2010.07.029.

Correction of T cell deficiency in ZAP-70 knock-out mice by simple intraperitoneal adoptive transfer of thymocytes.

Clin Exp Immunol. 2018 Jun;192(3):302-314. doi: 10.1111/cei.13114. Epub 2018 Mar 12.

Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome.

Blood. 2009 Jul 2;114(1):105-8. doi: 10.1182/blood-2009-03-211029. Epub 2009 May 4.

SYK expression endows human ZAP70-deficient CD8 T cells with residual TCR signaling.

Clin Immunol. 2015 Dec;161(2):103-9. doi: 10.1016/j.clim.2015.07.002. Epub 2015 Jul 14.

NF-κB-inducing kinase in thymic stroma establishes central tolerance by orchestrating cross-talk with not only thymocytes but also dendritic cells.

J Immunol. 2014 Nov 1;193(9):4356-67. doi: 10.4049/jimmunol.1400389. Epub 2014 Sep 26.

Reduced central tolerance in Omenn syndrome leads to immature self-reactive oligoclonal T cells.

J Allergy Clin Immunol. 2009 Oct;124(4):793-800. doi: 10.1016/j.jaci.2009.06.048. Epub 2009 Sep 19.

Identification of a novel mutation in ZAP70 and prenatal diagnosis in a Turkish family with severe combined immunodeficiency disorder.

Gene. 2013 Jan 10;512(2):189-93. doi: 10.1016/j.gene.2012.10.062. Epub 2012 Nov 2.

引用本文的文献

Mechanism study of ubiquitination in T cell development and autoimmune disease.

Front Immunol. 2024 Mar 18;15:1359933. doi: 10.3389/fimmu.2024.1359933. eCollection 2024.

Primary and secondary defects of the thymus.

Immunol Rev. 2024 Mar;322(1):178-211. doi: 10.1111/imr.13306. Epub 2024 Jan 16.

Inborn errors of immunity associated with defects of thymic development.

Pediatr Allergy Immunol. 2022 Aug;33(8):e13832. doi: 10.1111/pai.13832.

Inborn errors of thymic stromal cell development and function.

Semin Immunopathol. 2021 Feb;43(1):85-100. doi: 10.1007/s00281-020-00826-9. Epub 2020 Nov 30.

A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70.

J Exp Med. 2016 Feb 8;213(2):155-65. doi: 10.1084/jem.20150888. Epub 2016 Jan 18.

Regulatory T-Cell Development in the Human Thymus.

Front Immunol. 2015 Aug 3;6:395. doi: 10.3389/fimmu.2015.00395. eCollection 2015.

Immunodeficiency and immune dysregulation associated with proximal defects of T cell receptor signaling.

Curr Opin Immunol. 2014 Dec;31:97-101. doi: 10.1016/j.coi.2014.10.003. Epub 2014 Oct 25.

Rag defects and thymic stroma: lessons from animal models.

Front Immunol. 2014 Jun 2;5:259. doi: 10.3389/fimmu.2014.00259. eCollection 2014.

Advances in basic and clinical immunology in 2013.

J Allergy Clin Immunol. 2014 Apr;133(4):967-76. doi: 10.1016/j.jaci.2014.01.026. Epub 2014 Feb 28.

Partial defects of T-cell development associated with poor T-cell function.

J Allergy Clin Immunol. 2013 May;131(5):1297-305. doi: 10.1016/j.jaci.2013.01.020. Epub 2013 Mar 5.